Indications for Lung Biopsy
lesions on the chest radiograph
should be discussed in a
multidisciplinary meeting with a
respiratory physician and
radiologist at a minimum.
transthoracic lung biopsy (PTLB) should be
considered in the following:
enlarging solitary nodule or mass on the chest radiograph
which is not amenable to diagnosis by
bronchoscopy or CT shows it is unlikely to be
accessible by bronchoscopy.
in a patient not known to have malignancy or who has
had a prolonged remission or more than one
infiltrates, either single or multiple, for which no
diagnosis has been made by sputum or blood
culture, serology, or bronchoscopy.
following negative bronchoscopy.
Relative Contraindications to Lung Biopsy
Abnormalities of lung function,
Respiratory failure (including
Arterial and venous pulmonary
The uncooperative patient.
Complications of Lung Biopsy
Pneumothorax (20.5% of biopsies),
Pneumothorax requiring a
chest drain (3.1%),
Haemoptysis (5.3%), and
Manhire A, Charig M, Clelland C,
Gleeson F, Miller R, Moss H, Pointon K, Richardson C,
Sawicka E; BTS. Guidelines for radiologically guided
lung biopsy. Thorax. 2003 Nov;58(11):920-36.
The Diffuse Parenchymal Lung
Disease Group of British Thoracic Society. The
diagnosis, assessment and treatment of diffuse
parenchymal lung disease in adults. Introduction.
Thorax. 1999 Apr;54 Suppl 1:S1-14.
Created: June 11, 2006