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Criteria for the Diagnosis of Behets Disease

Finding

Definition

Recurrent oral ulceration

Minor aphthous, major aphthous, or herpetiform ulcers observed by the physician or patient, which have recurred at least three times over a 12-month period

Recurrent genital ulceration

Aphthous ulceration or scarring observed by the physician or patient

Eye lesions

Anterior uveitis, posterior uveitis, or cells in the vitreous on slit-lamp examination; or retinal vasculitis detected by an ophthalmologist

Skin lesions

Erythema nodosum observed by the physician or patient, pseudofolliculitis, or papulopustular lesions; or acneiform nodules observed by the physician in a postadolescent patient who is not receiving corticosteroids

Positive pathergy test

Test interpreted as positive by the physician at 24 to 48 hours

For the diagnosis to be made, a patient must have recurrent oral ulceration plus at least two of the other findings in the absence of other clinical explanations.

 

 

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References:

  1. O'Neill TW, Rigby AS, Silman AJ, Barnes C. Validation of the International Study Group criteria for Behçet's disease. Br J Rheumatol. 1994 Feb;33(2):115-7. [Medline]

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Created: Sep 10, 2007
Last Modified: 10/24/2010

 
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