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Names and definitions of vasculitis adopted by the Chapel Hill Consensus Conference

Names and definitions of vasculitis adopted by the Chapel Hill Consensus Conference on the nomenclature of systemic vasculitis

  1. Polyarteritis nodosa (PAN): Necrotizing inflammation of medium-sized or small arteries without glomerulonephritis or vasculitis in arterioles, capillaries or venules.
  2. Wegener´s granulomatosis (WG): Granulomatous inflammation involving the respiratory tract, and necrotizing vasculitis affecting small to medium-sized vessels, e. g. capillaries, venules, arterioles and arteries. Necrotizing glomerulonephritis is common.
  3. Churg-Strauss syndrome (CSS): Eosinophil-rich and granulomatous inflammation involving the respiratory tract and necrotizing vasculitis affecting small to medium-sized vessels, and associated with asthma and blood eosinophilia.
  4. Microscopic polyangiitis (MSA): Necrotizing vasculitis with few or no immune deposits affecting small vessels, i.e. capillaries, venules or arterioles. Necrotizing arteritis of small and medium-sized arteries may be present. Necrotizing glomerulonephritis is very common. Pulmonary capillaritis often occurs.

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References:

  1. Bruce IN, Bell AL. A comparison of two nomenclature systems for primary systemic vasculitis. Br J Rheumatol. 1997 Apr;36(4):453-8. [Medline]

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Created: May 29, 2005
Last Modified: 10/24/2010

 
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