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18th Edition (August 5, 2011)
|International Classification of Retinopathy of Prematurity|
|Written by G. Firman MD|
|Thursday, 08 July 2010 06:33|
The International Classification of Retinopathy of Prematurity (ICROP) was published in 2 parts, the first in 1984 and later expanded in 1987. It was a consensus statement of an international group of retinopathy of prematurity experts.
Retinopathy of Prematurity (ROP)
Four features are evaluated: zone, stage, extent, and presence or absence of plus disease.
Location of disease
The location of the retinopathy within the retina is defined by dividing the eye into three zones, centered on the optic nerve:
Staging the disease
Stage 5: Total retinal detachment
A is an open funnel.
Extent of disease
The extent of disease is described by dividing the retinal surface into 30º sectors, similar to the hours of a clock. As many as 12 clock hours can be affected, and the stage of retinopathy can vary among sectors.
Plus disease refers to dilation and tortuosity of the retinal arterioles and venules in the posterior pole of the retina as defined by a standard photograph. This indicates severe ROP, perhaps caused by excessive shunting of blood through the neovascular tissue at the ridge and often is followed by rapid progression to retinal detachment. Plus disease also may be a direct effect of excessive vascular endothelial growth factor (VEGF) acting on retinal blood vessels. Vitreous haze, engorgement of the iris vessels, and poor dilation of the pupil sometimes accompany plus disease, and often heralds rapid progression with poor prognosis.
Pre-plus disease is defined as dilation and tortuosity of the posterior pole arterioles and venules that are insufficient for the diagnosis of plus disease. It is the precursor to plus disease and in one study predicted progression to severe ROP that required treatment.
Involutional Sequelae Retinopathy of Prematurity
Created: Jul 08, 2010
|Last Updated on Wednesday, 21 December 2011 05:05|
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