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18th Edition (August 5, 2011)

Home Criteria Rheumatology Criteria for the Diagnosis of Behçet’s Disease


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Criteria for the Diagnosis of Behçet’s Disease Print E-mail
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Written by G. Firman MD   
Sunday, 22 February 2009 14:08


Recurrent oral ulcerationMinor aphthous, major aphthous, or herpetiform ulcers observed by the physician or patient, which have recurred at least three times over a 12-month period
Recurrent genital ulcerationAphthous ulceration or scarring observed by the physician or patient
Eye lesionsAnterior uveitis, posterior uveitis, or cells in the vitreous on slit-lamp examination; or retinal vasculitis detected by an ophthalmologist
Skin lesionsErythema nodosum observed by the physician or patient, pseudofolliculitis, or papulopustular lesions; or acneiform nodules observed by the physician in a postadolescent patient who is not receiving corticosteroids
Positive pathergy testTest interpreted as positive by the physician at 24 to 48 hours

 For the diagnosis to be made, a patient must have recurrent oral ulceration plus at least two of the other findings in the absence of other clinical explanations.



  1. O'Neill TW, Rigby AS, Silman AJ, Barnes C. Validation of the International Study Group criteria for Behçet's disease. Br J Rheumatol. 1994 Feb;33(2):115-7. [Medline]


Created: Sep 10, 2007


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