The diagnosis of a Functional Disorder of the Biliary Tract and Pancreas always pre-sumes the absence of a structural or biochemical explanation for the symptoms.

E1. Gallbladder Dysfunction

Episodes of severe steady pain located in the epigastrium and right upper quadrant, and all of the following:

1. Symptom episodes last 30 minutes or more, with pain-free intervals;
2. Symptoms have occurred on one or more occasions in the previous 12 months;
3. The pain is steady and interrupts daily activities or requires consultation with a physician;
4. There is no evidence of structural abnormalities to explain the symptoms; and
5. There is abnormal gallbladder functioning with regard to emptying.

E2. Sphincter of Oddi Dysfunction

Episodes of severe steady pain located in the epigastrium and right upper quadrant, and all of the following:

1. Symptom episodes last 30 minutes or more, with pain-free intervals;
2. Symptoms have occurred on one or more occasions in the previous 12 months;
3. The pain is steady and interrupts daily activities or requires consultation with a physician; and
4. There is no evidence of structural abnormalities to explain the symptoms.

1. Douglas A. Drossman. ROME II: The Functional Gastrointestinal Disorders, Second Edition

This material was taken from the ROME II. It is intended for educational purposes only.

Created: March 19, 2005