Once the clinical suspicion is established, the diagnosis is based on the combination of clinical, biochemical, endoscopic, histological and/or radiological criteria. Continue reading
Lennard-Jones Diagnostic Criteria of Crohn’s Disease (CD)
Ulcerative Colitis Activity Index
Ulcerative colitis (UC) is a chronic immune-mediated inflammatory condition of the large intestine that is frequently associated with inflammation of the rectum but often extends proximally to involve additional areas of the colon. Once a diagnosis of UC is made, determining the severity of disease becomes important. Continue reading
Diagnostic Criteria for Idiopathic Intracranial Hypertension (IIH)
The combination of raised intracranial pressure, without hydrocephalus or mass lesion, normal cerebrospinal fluid (CSF) composition and where no underlying aetiology is found are accepted criteria for the diagnosis of IIH. Continue reading
Indications for Intracranial Pressure Monitoring
Monitoring of Intracranial Pressure (ICP) is an invasive technique and has some associated risks. For a favorable risk-to-benefit ratio, ICP monitoring is indicated only in patients with significant risk of intracranial hypertension. Continue reading
DSM-5 Criteria for Female Sexual Interest/Arousal Disorder
Female sexual dysfunction (FSD) is a general term comprising several sexual health concerns that can be distressing for patients, including female sexual interest/arousal disorder, female orgasmic disorder, and genito-pelvic pain/penetration disorder. Continue reading
Revised Diagnostic Criteria for Preeclampsia
Preeclampsia is a disorder of pregnancy associated with new-onset hypertension, which occurs most often after 20 weeks of gestation and frequently near term. Although often accompanied by new-onset proteinuria, hypertension and other signs or symptoms of preeclampsia may present in some women in the absence of proteinuria. Continue reading
Updated Diagnostic Criteria for Tuberous Sclerosis Complex (TSC)
Tuberous sclerosis complex (TSC) is highly variable in clinical presentation and findings. Disease manifestations continue to develop over the lifetime of an affected individual. Accurate diagnosis is fundamental to implementation of appropriate medical surveillance and treatment. Continue reading
Diagnostic Criteria for Sarcopenia
Sarcopenia is a progressive and generalised skeletal muscle disorder that is associated with increased likelihood of adverse outcomes including falls, fractures, physical disability and mortality. Continue reading
Diagnostic Criteria for Vasospastic Angina (VSA)
Vasospastic angina (VSA) is a variant form of angina pectoris, in which angina occurs at rest, with transient electrocardiogram modifications and preserved exercise capacity. VSA can be involved in many clinical scenarios, such as stable angina, sudden cardiac death, acute coronary syndrome, arrhythmia or syncope. Continue reading
ASAS Categorization Criteria for Spondyloarthritis
Assessment in SpondyloArthritis international Society (ASAS) criteria were validated in an international cohort trial with a sensibility and specificity close to 82.9 and 84.4%, respectively. Continue reading