HMG CoA-reductase inhibitors or statins are clearly the most effective class of drugs for lowering LDL cholesterol. Those drugs have been associated with a beneficial impact on cardiovascular morbidity and mortality.
PVD can be categorized using the Fontaine or Rutherford classification system. Each system grades PVD from no symptoms to major tissue loss and can be used at diagnosis and to evaluate the progression or improvement of symptoms.
The Ross Heart Failure Classification was developed to provide a global assessment of heart failure severity in infants, and has subsequently been modified to apply to all pediatric ages. The modified Ross Classification incorporates feeding difficulties, growth problems, and symptoms of exercise intolerance into a numeric score comparable with the NYHA classification for adults.
Recently, the term “autoreactive pericarditis” has been introduced to describe patients with identification of elements indicative of an autoimmune response who would otherwise be classed as idiopathic.
The recommended classification is unchanged from the 2003 and 2007 ESH/ESC guidelines. Hypertension is defined as values >/=140 mmHg systolic blood pressure (SBP) and/or >/=90 mmHg diastolic blood pressure (DBP), based on the evidence from randomized controlled trials (RCTs) that in patients with these blood pressure (BP) values treatment-induced BP reductions are beneficial.
There are numerous potential clinical uses of the 12-lead ECG. The ECG may reflect changes associated with primary or secondary myocardial processes (e.g., those associated with coronary artery disease, hypertension, cardiomyopathy, or infiltrative disorders), metabolic and electrolyte abnormalities, and therapeutic or toxic effects of drugs or devices. Electrocardiography serves as the gold standard for the noninvasive diagnosis of arrhythmias and conduction disturbances, and it occasionally is the only marker for the presence of heart disease.