Universal Definitions of Myocardial Injury and Myocardial Infarction

With the introduction of more sensitive cardiac biomarkers, the European Society of Cardiology (ESC) and the American College of Cardiology (ACC) collaborated to redefine MI using a biochemical and clinical approach, and reported that myocardial injury detected by abnormal biomarkers in the setting of acute myocardial ischaemia should be labelled as MI. Continue reading

Recommendations for Management of Hypertension (JNC 8)

Hypertension is the most common condition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if not detected early and treated appropriately. Patients want to be assured that blood pressure (BP) treatment will reduce their disease burden, while clinicians want guidance on hypertension management using the best scientific evidence. Continue reading

2018 ESC/ESH Classification of Arterial Hypertension

The relationship between BP and cardiovascular (CV) and renal events is continuous, making the distinction between normotension and hypertension, based on cut-off BP values, somewhat arbitrary. However, in practice, cut-off BP values are used for pragmatic reasons to simplify the diagnosis and decisions about treatment. Continue reading

Comparative Effectiveness of Statin Therapy

HMG CoA-reductase inhibitors or statins are clearly the most effective class of drugs for lowering LDL cholesterol. Those drugs have been associated with a beneficial impact on cardiovascular morbidity and mortality.

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NYHA and Modified Ross Heart Failure Classification for Children

The Ross Heart Failure Classification was developed to provide a global assessment of heart failure severity in infants, and has subsequently been modified to apply to all pediatric ages. The modified Ross Classification incorporates feeding difficulties, growth problems, and symptoms of exercise intolerance into a numeric score comparable with the NYHA classification for adults.

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Definitions and Classification of Office Blood Pressure Levels (2013 ESH/ESC)

The recommended classification is unchanged from the 2003 and 2007 ESH/ESC guidelines. Hypertension is defined as values >/=140 mmHg systolic blood pressure (SBP) and/or >/=90 mmHg diastolic blood pressure (DBP), based on the evidence from randomized controlled trials (RCTs) that in patients with these blood pressure (BP) values treatment-induced BP reductions are beneficial.

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