Scoring system for risk of complications among febrile neutropenic patients, based on the Multinational Association for Supportive Care in Cancer (MASCC) predictive model.
| Characteristic | Point score |
|
Burden of illness *No or mild symptoms *Moderate symptoms |
5 3 |
| No hypotension | 5 |
| No chronic obstructive pulmonary disease | 4 |
| Solid tumor or no previous fungal infection in hematologic tumor | 4 |
| Outpatient status | 3 |
| No dehydration | 3 |
| Aged <60 years | 2 |
The maximum value in this system is 26, and a score of <21 predicts a <5% risk for severe complications and a very low mortality (<1%) in febrile neutropenic patients.
References:
- Klastersky J. Management of fever in neutropenic patients with different risks of complications. Clin Infect Dis. 2004 Jul 15;39 Suppl 1:S32-7. [Medline]
- Antoniadou A, Giamarellou H. Fever of unknown origin in febrile leukopenia. Infect Dis Clin North Am. 2007 Dec;21(4):1055-90. [Medline]
Created: Sep 03, 2008
