ROME II Diagnostic Criteria for Functional Gastroduodenal Disorders

The diagnosis of a Functional Gastroduodenal Disorder always presumes the absence of a structural or biochemical explanation for the symptoms.

B1. Functional Dyspepsia

At least 12 weeks, which need not be consecutive, in the preceding 12 months of:

  1. Persistent or recurrent symptoms (pain or discomfort centered in the upper abdomen);
  2. No evidence of organic disease (including at upper endoscopy) that is likely to explain the symptoms; and
  3. No evidence that dyspepsia is exclusively relieved by defecation or associated with the onset of a change in stool frequency or stool form (i.e., not irritable bowel).

B1a. Ulcer-like Dyspepsia

Pain centered in the upper abdomen is the predominant (most bother-some) symptom.

B1b. Dysmotility-like Dyspepsia

An unpleasant or troublesome nonpainful sensation (discomfort) centered in the upper abdomen is the predominant symptom; this sensation may be characterized by or associated with upper abdominal fullness, early satiety, bloating, or nausea.

B1c. Unspecified (Nonspecific) Dyspepsia

Symptomatic patients whose symptoms do not fulfill the criteria for ulcer-like or dysmotility-like dyspepsia.

B2. Aerophagia

At least 12 weeks, which need not be consecutive, in the preceding 12 months of:

  1. Air swallowing that is objectively observed; and
  2. Troublesome repetitive belching.

B3. Functional Vomiting

At least 12 weeks, which need not be consecutive, in the preceding 12 months of:

  1. Frequent episodes of vomiting, occurring on at least three separate days in a week over three months;
  2. Absence of criteria for an eating disorder, rumination, or major psychiatric disease according to DSM-IV;
  3. Absence of self-induced and medication-induced vomiting; and
  4. Absence of abnormalities in the gut or central nervous system, and metabolic diseases to explain the recurrent vomiting.

References:

  1. Douglas A. Drossman. ROME II: The Functional Gastrointestinal Disorders, Second Edition

This material was taken from the ROME II. It is intended for educational purposes only.

Created: March 19, 2005

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