MASCC Index Score for Identifying Low-Risk Febrile Neutropenic Cancer Patients

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Scoring system for risk of complications among febrile neutropenic patients, based on the Multinational Association for Supportive Care in Cancer (MASCC) predictive model.

Characteristic

Point score

Burden of illness

*No or mild symptoms

*Moderate symptoms

5

3

No hypotension

5

No chronic obstructive pulmonary disease

4

Solid tumor or no previous fungal infection in hematologic tumor

4

Outpatient status

3

No dehydration

3

Aged <60 years

2

The maximum value in this system is 26, and a score of <21 predicts a <5% risk for severe complications and a very low mortality (<1%) in febrile neutropenic patients.

 
 

References:

  1. Klastersky J. Management of fever in neutropenic patients with different risks of complications. Clin Infect Dis. 2004 Jul 15;39 Suppl 1:S32-7. [Medline]

  2. Antoniadou A, Giamarellou H. Fever of unknown origin in febrile leukopenia. Infect Dis Clin North Am. 2007 Dec;21(4):1055-90. [Medline]

Created: Sep 03, 2008