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Diagnostic Criteria for Transient Global Amnesia (TGA)

Transient global amnesia (TGA) is a benign, temporary loss of anterograde memory with sparing of immediate recall and remote memories.

Diagnostic Criteria for Transient Global Amnesia (TGA)
In order to diagnose TGA the patient must satisfy the following criteria, created by Hodge and Warlow in 1990:

  1. The attack was witnessed and reported.
  2. There was obvious anterograde amnesia during the attack.
  3. There was an absence of clouding of consciousness.
  4. There were no focal neurological signs or deficits during or after the attack.
  5. There were no features of epilepsy.
  6. The attack resolved within 24h.
  7. The patient did not have any recent head injury or active epilepsy.
Adapted from Caplan
  1. Attack is witnessed
  2. Dysfunction limited to repetitive queries and amnesia
  3. No other major neurologic signs or symptoms
  4. Memory loss is transient, usually lasting hours to a day

 

References:

  1. Arena JE, Rabinstein AA. Transient global amnesia. Mayo Clin Proc. 2015 Feb;90(2):264-72. [Medline]
  2. Harrison M, Williams M. The diagnosis and management of transient global amnesia in the emergency department. Emerg Med J. 2007 Jun;24(6):444-5[Medline]
  3. Owen D, Paranandi B, Sivakumar R, Seevaratnam M. Classical diseases revisited: transient global amnesia. Postgraduate Medical Journal. 2007;83(978):236-239. [Medline]
  4. Hodges JR, Warlow CP. Syndromes of transient amnesia: towards a classification. A study of 153 cases. J Neurol Neurosurg Psychiatry. 1990 Oct;53(10):834-43. [Medline]
  5. Ropper AH. Transient Global Amnesia. N Engl J Med. 2023 Feb 16;388(7):635-640. [Medline]

 

Created: Dec 23, 2015.
Update: Sep 08, 2023.

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