First introduced in 1989, proton pump inhibitors (PPIs) are among the most widely utilized medications worldwide, both in the ambulatory and inpatient clinical settings. The PPIs are currently approved by the US Food and Drug Administration (FDA) for the management of a variety of gastrointestinal disorders including symptomatic peptic ulcer disease, gastroesophageal reflux disease, and nonulcer dyspepsia as well as for prevention of gastrointestinal bleeding in patients receiving antiplatelet therapy.
Food and Drug Administration Approved Indications for Proton Pump Inhibitors
NASID, nonsteroidal anti-inflammatory drugs; GI, gastrointestinal; IV, intravenous; NG, nasogastric.
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Created Nov 15, 2018.