ASAS Categorization Criteria for Spondyloarthritis

Assessment in SpondyloArthritis international Society (ASAS) criteria were validated in an international cohort trial with a sensibility and specificity close to 82.9 and 84.4%, respectively.

 

ASAS Categorization Criteria for Spondyloarthritis

ASAS Categorization Criteria for spondyloarthritis (SpA) in patients under 45 years old of age with lower back pain of 3 months duration.

  • Radiological diagnosis of sacroiliitis + 1 or more features of spondyloarthritis

OR

  • HLA B27 + 2 or more features of spondyloarthritis

Features of spondyloarthritis

  • Low inflammatory pain
  • Arthritis
  • Enthesitis
  • Uveítis
  • Dactilitis
  • Psoriasis
  • Crohn/colitis
  • Good response to NSAIDs
  • Family history of spondyloarthropathy
  • HLA B27
  • High CRP levels

Radiological diagnosis of sacroiliitis

  • Active (acute) inflammation in the MRI highly suggestive of sacroiliitis due to SpA
  • Radiological sacroiliitis defined according to the New York criteria (grade >2 bilateral or grade 3-4 unilateral)

 

References:

  1. Lambert RG, Bakker PA, van der Heijde D, Weber U, Rudwaleit M, Hermann KG, Sieper J, Baraliakos X, Bennett A, Braun J, Burgos-Vargas R, Dougados M, Pedersen SJ, Jurik AG, Maksymowych WP, Marzo-Ortega H, Østergaard M, Poddubnyy D, Reijnierse M, van den Bosch F, van der Horst-Bruinsma I, Landewé R. Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group. Ann Rheum Dis. 2016 Nov;75(11):1958-1963. [Medline]
  2. Banegas Illescas ME, López Menéndez C, Rozas Rodríguez ML, Fernández Quintero RM. New ASAS criteria for the diagnosis of spondyloarthritis: diagnosing sacroiliitis by magnetic resonance imaging. Radiologia. 2014 Jan-Feb;56(1):7-15. [Medline]
  3. Sieper J, Rudwaleit M, Baraliakos X, Brandt J, Braun J, Burgos-Vargas R, Dougados M, Hermann KG, Landewé R, Maksymowych W, van der Heijde D. The Assessment of SpondyloArthritis international Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis. 2009 Jun;68 Suppl 2:ii1-44. [Medline]

Created: Aug 16, 2019.