Diagnostic Criteria of Primary Sclerosing Cholangitis (PSC)

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown cause that is characterized pathologically by an inflammatory and fibrotic process centered on the epithelium, leading to diffuse biliary stenosis and increased wall thickness throughout the intra- and extra-hepatic biliary trees.

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Diagnostic Criteria for Cholangitis

Diagnostic criteria of acute cholangitis: Tokyo Guidelines

A. Clinical context and clinical manifestations

1. History of biliary disease
2. Fever and/or chills
3. Jaundice
4. Abdominal pain (right upper quadrant or upper abdominal)
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