Clinical Conditions Associated with Disseminated Intravascular Coagulation (DIC)
1. Sepsis/severe infection (any microorganism)
2. Trauma (e.g., polytrauma, neurotrauma, fat embolism)
3. Organ destruction (e.g., severe pancreatitis)
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Diagnostic Criteria for Disseminated Intravascular Coagulation (DIC)
Disseminated intravascular coagulation is a condition in which small blood clots develop throughout the bloodstream, blocking small blood vessels. The increased clotting depletes the platelets and clotting factors needed to control bleeding, causing excessive bleeding.