The European Spondyloarthropathy Study Group (ESSG) Classification for Spondyloarthropathy (SpA)

According to the ESSG criteria, for a patient to be classified as having SpA, he or she has to satisfy one of two entry criteria: Inflammatory spinal pain OR synovitis that is either asymmetric or predominantly in the lower limbs.

  • Inflammatory back pain: Back pain is common among the general population. However, “inflammatory” back pain is much less common. Back pain is considered inflammatory if four of the following five criteria are found:

    1. Onset of back discomfort before the age of 40 years

    2. Insidious onset

    3. Persistence for at least three months

    4. Associated with morning stiffness

    5. Improvement with exercise

  • Asymmetrical synovitis: Asymmetrical synovitis, predominantly of the lower limbs is manifested by soft tissue swelling, warmth over a joint, joint effusion, and reductions in both active and passive range of motion. As with inflammatory spinal pain, the symptoms are worse after a period of rest.

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Revised International Classification Criteria for Sjögren’s Syndrome (SS)

I. Ocular symptoms: a positive response to at least one of the following questions:

  1. Have you had daily, persistent, troublesome dry eyes for more than 3 months?

  2. Do you have a recurrent sensation of sand or gravel in the eyes?

  3. Do you use tear substitutes more than 3 times a day?

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Criteria for the Classification of Systemic Sclerosis (Scleroderma)

1980 Criteria for the Classification of Systemic Sclerosis

The American College of Rheumatology (former American Rheumatism Association – ARA) has defined criteria, that are 97 % sensitive and 98 % specific for systemic sclerosis (SSc) as follows:

Major criterion:

  • Proximal diffuse (truncal) sclerosis (skin tightness, thickening, non-pitting induration)

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Classification of Neutrophilia

Primary (no other evident associated disease)

    • Hereditary neutrophilia
    • Chronic idiopathic neutrophilia
    • Chronic myelogenous leukemia (CML) and other myeloproliferative diseases
    • Familial myeloproliferative disease
    • Congenital anomalies and leukemoid reaction
    • Leukocyte adhesion deficiency (LAD)
    • Familial cold urticaria and leukocytosis

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Classification of Neutropenia

Acquired neutropenia

    • Postinfectious: varicella, measles, rubella, hepatitis A and B, mononucleosis, influenza, cytomegalovirus, parvovirus, acquired immunodeficiency syndrome (AIDS), S. aureus, brucellosis, tularemia, rickettsia, Mycobacterium tuberculosis, sepsis.
    • Drug induced: Antineoplastic agents, procainamide, antithyroid drugs, sulphasalazine, phenothiazines, semisynthetic penicillins, nonsteroidal anti-inflammatory agents, aminopyrine derivatives, benzodiazepines, barbiturates, gold compounds, sulfonamides, propranolol, dipyridamole, digoxin, acetyldigoxin, sulfamethoxizole, anticonvulsants
    • Benign familial neutropenia
    • Chronic benign neutropenia of childhood
    • Chronic idiopathic neutropenia
    • Autoimmune neutropenia
    • Isoimmune neutropenia
    • Neutropenia associated with immunologic abnormalities
    • Neutropenia associated with metabolic diseases
    • Neutropenia due to increased margination
    • Nutritional deficiency

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FAB Classification of Myelodysplastic Syndromes (MDS)

Refractory anemia (RA).

  • Cytopenia of at least one lineage in the peripheral blood (usually anemia)

  • Normal or hypercellular bone marrow with dysplastic changes

  • Less than 1 percent blasts in the peripheral blood and less than 5 percent blasts in the bone marrow

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Classification Criteria for the Diagnosis of Systemic Lupus Erythematosus (SLE)

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown cause that can affect virtually any organ of the body. Immunologic abnormalities, especially the production of a number of antinuclear antibodies (ANA), are a prominent feature of the disease. Continue reading