Classification of Neutrophilia

Primary (no other evident associated disease)

    • Hereditary neutrophilia
    • Chronic idiopathic neutrophilia
    • Chronic myelogenous leukemia (CML) and other myeloproliferative diseases
    • Familial myeloproliferative disease
    • Congenital anomalies and leukemoid reaction
    • Leukocyte adhesion deficiency (LAD)
    • Familial cold urticaria and leukocytosis

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Classification of Neutropenia

Acquired neutropenia

    • Postinfectious: varicella, measles, rubella, hepatitis A and B, mononucleosis, influenza, cytomegalovirus, parvovirus, acquired immunodeficiency syndrome (AIDS), S. aureus, brucellosis, tularemia, rickettsia, Mycobacterium tuberculosis, sepsis.
    • Drug induced: Antineoplastic agents, procainamide, antithyroid drugs, sulphasalazine, phenothiazines, semisynthetic penicillins, nonsteroidal anti-inflammatory agents, aminopyrine derivatives, benzodiazepines, barbiturates, gold compounds, sulfonamides, propranolol, dipyridamole, digoxin, acetyldigoxin, sulfamethoxizole, anticonvulsants
    • Benign familial neutropenia
    • Chronic benign neutropenia of childhood
    • Chronic idiopathic neutropenia
    • Autoimmune neutropenia
    • Isoimmune neutropenia
    • Neutropenia associated with immunologic abnormalities
    • Neutropenia associated with metabolic diseases
    • Neutropenia due to increased margination
    • Nutritional deficiency

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FAB Classification of Myelodysplastic Syndromes (MDS)

Refractory anemia (RA).

  • Cytopenia of at least one lineage in the peripheral blood (usually anemia)

  • Normal or hypercellular bone marrow with dysplastic changes

  • Less than 1 percent blasts in the peripheral blood and less than 5 percent blasts in the bone marrow

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Classification Criteria for the Diagnosis of Systemic Lupus Erythematosus (SLE)

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown cause that can affect virtually any organ of the body. Immunologic abnormalities, especially the production of a number of antinuclear antibodies (ANA), are a prominent feature of the disease. Continue reading

ICSD Revised Classification of Adult Insomnia

Primary Insomnia

  • Idiopathic insomnia: Insomnia arising in infancy or childhood with a persistent, unremitting course
  • Psychophysiologic insomnia: Insomnia due to a maladaptive conditioned response in which the patient  learns to associate the bed environment with heightened arousal rather than sleep; onset often associated with an event causing acute insomnia, with the sleep disturbance persisting despite resolution of the precipitating factor
  • Paradoxical insomnia (sleep-state misperception): Insomnia characterized by a marked mismatch between the patients description of sleep duration and objective polysomnographic findings Continue reading