Criteria to Initiate Evaluation for Growth Hormone Deficiency (GHD)

Tools for the diagnosis of GHD include auxology, radiographic assessment of bone age, measurement of insulin-like growth factor 1 (IGF-I) and IGF binding protein 3 (IGFBP-3), provocative growth hormone (GH) testing, cranial magnetic resonance imaging (MRI), and, in certain cases, genetic testing. Growth velocity and the degree of short stature are primary considerations in the decision to pursue evaluation for GHD. Continue reading

Allred Score for Estrogen and Progesterone Receptor Evaluation

Breast cancer (BC) hormonal receptors status is assessed by immunohistochemistry (IHC), a specific, sensitive, and accessible method that guide breast cancer treatment. Continue reading

Perioperative Cardiovascular Evaluation for Noncardiac Surgery

Clinical Predictors of Increased Perioperative Cardiovascular Risk (Myocardial Infarction, Heart Failure, Death)

Major

  • Unstable coronary syndromes
    • Acute or recent MI* with evidence of important ischemic risk by clinical symptoms or noninvasive study
    • Unstable or severe† angina (Canadian class III or IV) Continue reading