Revised IMWG Diagnostic Criteria for Multiple Myeloma

The International Myeloma Working Group (IMWG) consensus updates the disease definition of multiple myeloma to include validated biomarkers in addition to existing requirements of attributable CRAB features (hypercalcaemia, renal failure, anaemia, and bone lesions). Continue reading

The European Spondyloarthropathy Study Group (ESSG) Classification for Spondyloarthropathy (SpA)

According to the ESSG criteria, for a patient to be classified as having SpA, he or she has to satisfy one of two entry criteria: Inflammatory spinal pain OR synovitis that is either asymmetric or predominantly in the lower limbs.

  • Inflammatory back pain: Back pain is common among the general population. However, “inflammatory” back pain is much less common. Back pain is considered inflammatory if four of the following five criteria are found:

  1. Onset of back discomfort before the age of 40 years

  2. Insidious onset

  3. Persistence for at least three months

  4. Associated with morning stiffness

  5. Improvement with exercise

  • Asymmetrical synovitis: Asymmetrical synovitis, predominantly of the lower limbs is manifested by soft tissue swelling, warmth over a joint, joint effusion, and reductions in both active and passive range of motion. As with inflammatory spinal pain, the symptoms are worse after a period of rest.

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