Primary, secondary, and tertiary preventive measures may reduce the incidence and severity of sensitizer-induced asthma.
Contrast-induced nephropathy (CIN) is defined as the impairment of renal function and is measured as either a 25% increase in serum creatinine (SCr) from baseline or 0.5 mg/dL (44 umol/L) increase in absolute value, within 48-72 hours of intravenous contrast administration. Continue reading
Diagnostic Criteria for Heparin-Induced Thrombocytopenia (HIT)
- Heparin exposure >5 days
- Relative thrombocytopenia: decrease in platelet count by 50% from baseline OR absolute thrombocytopenia: decrease in platelet count to less than 100 to 150 x 109/L
- Absence of other causes of thrombocytopenia
- Development of new thrombosis, or extension of pre-existing thrombosis, while receiving heparin therapy
- Confirmation by laboratory testing
- Return to normal platelet count when heparin is discontinued Continue reading
The clinical diagnosis of amiodarone-induced pulmonary toxicity (APT) requires two or more of the following criteria:
- new onset of pulmonary symptoms such as dyspnea, cough, or pleuritic chest pain;
- new chest radiographic abnormality such as an interstitial or alveolar infiltrate;
- a decrease in the DLCO of 20% from the pretreatment value, or if none is available, a value less than 80% of predicted;
- abnormal lung uptake with gallium-67 radioisotope; and
- characteristic histologic changes of lung tissue obtained by bronchoscopic or open lung biopsy.