Staging and Risk Stratification of Germ-Cell Tumors

Germ cell tumours of the testis are the commonest malignancy in men aged 20-40 years. Considerable therapeutic improvements in management-based on the cancer’s responsiveness to chemotherapy that contains platinum-mean that over 95% of these patients can now expect to be cured.

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Summary of the ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce ASCVD

The updated American College of Cardiology/American Heart Association (ACC/AHA) Guideline on the Treatment of Blood Cholesterol (GTBC) has been long-awaited since the latest update of the Adult Treatment Panel III (ATP III) guidelines in 2004. The updated GTBC recommends a significant paradigm shift in lipid-lowering drug therapy for atherosclerotic cardiovascular disease (ASCVD) risk reduction, which has led to questions regarding their content and their implementation.

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Risk Factors for Contrast-Induced Nephropathy (CIN)

Contrast-induced nephropathy (CIN) is defined as the impairment of renal function and is measured as either a 25% increase in serum creatinine (SCr) from baseline or 0.5 mg/dL (44 umol/L) increase in absolute value, within 48-72 hours of intravenous contrast administration. Continue reading

TIMI Risk Score for ST-Elevation Myocardial Infarction (STEMI)

The TIMI risk score, based upon data from 15,000 patients with an ST segment elevation myocardial infarction eligible for fibrinolytic therapy, is a simple arithmetic sum of eight independent predictors of mortality.

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Criteria for Evaluating the Effectiveness of Screening for a Risk Factor

Characteristics of the disease

1. Disease has serious consequences

2. Screening population has a high incidence* of disease

3. Risk factor is a good predictor of disease

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MASCC Index Score for Identifying Low-Risk Febrile Neutropenic Cancer Patients

Scoring system for risk of complications among febrile neutropenic patients, based on the Multinational Association for Supportive Care in Cancer (MASCC) predictive model.

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Estimate of 10-Year Risk for Coronary Heart Disease for Women (Framingham Point Scores)

Coronary Heart Disease (CHD) score sheet for women using TC or LDL-C categories. Uses age, TC, HDL-C, blood pressure, diabetes, and smoking. Estimates risk for CHD over a period of 10 years based on Framingham experience in women 30 to 74 years old at baseline. Average risk estimates are based on typical Framingham subjects, and estimates of idealized risk are based on optimal blood pressure, TC 160 to 199 mg/dL (or LDL 100 to 129 mg/dL), HDL-C of 55 mg/dL in women, no diabetes, and no smoking. Use of the LDL-C categories is appropriate when fasting LDL-C measurements are available. Pts indicates points.

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Estimate of 10-Year Risk for Coronary Heart Disease for Men (Framingham Point Scores)

Coronary Heart Disease (CHD) score sheet for men using TC or LDL-C categories. Uses age, TC (or LDL-C), HDL-C, blood pressure, diabetes, and smoking. Estimates risk for CHD over a period of 10 years based on Framingham experience in men 30 to 74 years old at baseline. Average risk estimates are based on typical Framingham subjects, and estimates of idealized risk are based on optimal blood pressure, TC 160 to 199 mg/dL (or LDL 100 to 129 mg/dL), HDL-C of 45 mg/dL in men, no diabetes, and no smoking. Use of the LDL-C categories is appropriate when fasting LDL-C measurements are available. Pts indicates points.

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Clinical and Laboratory “Low Risk” Criteria for Children Younger Than 3 Months with Fever and No Focus of Infection

Clinical criteria

  • Born at term (gestational age >/= 37 weeks)with uncomplicated nursery stay
  • Previously healthy infants
  • No toxic manifestations
  • No focal bacterial infection (except otitis media) Continue reading

Cardiovascular Major Risk Factors

Cardiovascular Major Risk Factors
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