Diagnostic Criteria and Severity Grading of Acute Cholecystitis (TG18)

The diagnostic criteria for acute cholecystitis have high sensitivity (91.2%) and specificity (96.9%) and good diagnostic yield; therefore, their use as the diagnostic criteria for acute cholecystitis is recommended.

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Severity Criteria for Clostridium difficile Infection

Patients with severe disease may develop a colonic ileus or toxic dilatation and present with abdominal pain and distension but with minimal or no diarrhea. Complications of severe C. difficile colitis include dehydration, electrolyte disturbances, hypoalbuminemia, toxic megacolon, bowel perforation, hypotension, renal failure, systemic inflammatory response syndrome, sepsis, and death.

Diagnosis and Determination of Severity of Acute Cholecystitis

Acute cholecystitis is a very common complication of cholelithiasis, and as such is frequently encountered in surgical practice. TG07 diagnostic criteria are recognized as those to be recommended in current care for acute cholecystitis.

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International Clinical Diabetic Retinopathy and Diabetic Macular Edema Disease Severity Scales

The levels in this new diabetic retinopathy disease severity scale consist of five scales with increasing risks of retinopathy.

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CURB-65 and CRB-65 Severity Scores for Community-Acquired Pneumonia (CAP)

CURB and CRB-65 scores can be used in the hospital and out-patients setting to assess pneumonia severity and the risk of death.

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Severity Criteria for Acute Pancreatitis

Ranson Criteria to Predict Severity of Acute Pancreatitis

1. When three or more of the following are present on admission, a severe course complicated by pancreatic necrosis can be predicted with a sensitivity of 60-80%:

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Child-Pugh Classification of Severity of Liver Disease

Modified Child-Pugh classification of severity of liver disease according to the degree of ascites, the plasma concentrations of bilirrubin and albumin, the prothrombin time, and the degree of encephalopathy.

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GOLD Staging System for Chronic Obstructive Lung Disease (COPD) Severity

The European Respiratory Society (ERS) diagnostic criteria for COPD include the following symptoms: coughing, sputum production and/or dyspnoea, as well as a history of exposure to risk factors for COPD. The diagnosis is confirmed by a post-bronchodilator FEV1/FVC < 0.7 in spirometry, as sign of the airflow limitation that is not fully reversible.

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GINA Classification of Asthma Severity

The Global Initiative for Asthma (GINA) works with health care professionals and public health officials around the world to reduce asthma prevalence, morbidity, and mortality. The gold standard in classifying severity of asthma is the GINA classification.

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The APACHE II Severity of Disease Classification System

APACHE II uses a point score based upon initial values of 12 routine physiologic measurements, age, and previous health status to provide a general measure of severity of disease.

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