Severity Criteria for Clostridium difficile Infection

Patients with severe disease may develop a colonic ileus or toxic dilatation and present with abdominal pain and distension but with minimal or no diarrhea. Complications of severe C. difficile colitis include dehydration, electrolyte disturbances, hypoalbuminemia, toxic megacolon, bowel perforation, hypotension, renal failure, systemic inflammatory response syndrome, sepsis, and death.

Diagnosis and Determination of Severity of Acute Cholecystitis

Acute cholecystitis is a very common complication of cholelithiasis, and as such is frequently encountered in surgical practice. TG07 diagnostic criteria are recognized as those to be recommended in current care for acute cholecystitis.

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International Clinical Diabetic Retinopathy and Diabetic Macular Edema Disease Severity Scales

The levels in this new diabetic retinopathy disease severity scale consist of five scales with increasing risks of retinopathy.

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GOLD Staging System for Chronic Obstructive Lung Disease (COPD) Severity

The European Respiratory Society (ERS) diagnostic criteria for COPD include the following symptoms: coughing, sputum production and/or dyspnoea, as well as a history of exposure to risk factors for COPD. The diagnosis is confirmed by a post-bronchodilator FEV1/FVC < 0.7 in spirometry, as sign of the airflow limitation that is not fully reversible.

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Classification and Severity of Angina

Class I

No angina with ordinary physical activity (e.g., walking, climbing stairs). Angina with strenuous or prolonged exertion.

Class II

Early-onset limitation of ordinary activity (e.g., walking rapidly or walking >2 blocks; climbing stairs rapidly or climbing >1 flight); angina may be worse after meals, in cold temperatures, or with emotional stress.

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