Hepatic sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) is a life-threatening complication of hematopoietic cell transplantation (HCT) that belongs to a group of diseases increasingly identified as transplant-related, systemic endothelial diseases. In most cases, SOS/VOD resolves within weeks; however, severe SOS/VOD results in multi-organ dysfunction/failure with a mortality rate >80%. Continue reading
The diagnostic criteria for acute cholecystitis have high sensitivity (91.2%) and specificity (96.9%) and good diagnostic yield; therefore, their use as the diagnostic criteria for acute cholecystitis is recommended.
Acute cholecystitis is a very common complication of cholelithiasis, and as such is frequently encountered in surgical practice. TG07 diagnostic criteria are recognized as those to be recommended in current care for acute cholecystitis.
The levels in this new diabetic retinopathy disease severity scale consist of five scales with increasing risks of retinopathy.
CURB and CRB-65 scores can be used in the hospital and out-patients setting to assess pneumonia severity and the risk of death.
Ranson Criteria to Predict Severity of Acute Pancreatitis
1. When three or more of the following are present on admission, a severe course complicated by pancreatic necrosis can be predicted with a sensitivity of 60-80%:
Modified Child-Pugh classification of severity of liver disease according to the degree of ascites, the plasma concentrations of bilirrubin and albumin, the prothrombin time, and the degree of encephalopathy.
The European Respiratory Society (ERS) diagnostic criteria for COPD include the following symptoms: coughing, sputum production and/or dyspnoea, as well as a history of exposure to risk factors for COPD. The diagnosis is confirmed by a post-bronchodilator FEV1/FVC < 0.7 in spirometry, as sign of the airflow limitation that is not fully reversible.
The Global Initiative for Asthma (GINA) works with health care professionals and public health officials around the world to reduce asthma prevalence, morbidity, and mortality. The gold standard in classifying severity of asthma is the GINA classification.