Normal dietary consumption and absorption of copper exceed the metabolic need, and homeostasis of this element is maintained exclusively by the biliary excretion of copper. Wilson’s disease is an inherited disorder in which defective biliary excretion of copper leads to its accumulation, particularly in liver and brain. Continue reading “Diagnostic Scoring System for Wilson’s Disease”
In 1968, Wilson and Jungner published 10 “principles” for evaluating screening programs, criteria widely used since then.
Continue reading “Wilson and Jungner Criteria for Screening”
Fat embolism syndrome, a condition characterized by hypoxia, bilateral pulmonary infiltrates, and mental status change.
Continue reading “Criteria for Diagnostic of Fat Embolism Syndrome (FES)”
Wilson’s disease is clinically characterised by hepatic and neurological manifestations related to the accumulation of copper in the liver and the lenticular nuclei, and by Kayser-Fleischer rings. Continue reading “Diagnostic Criteria for Wilson’s disease”
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