{"id":2526,"date":"2009-03-05T18:21:43","date_gmt":"2009-03-05T18:21:43","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/hempv\/"},"modified":"2025-05-14T19:10:53","modified_gmt":"2025-05-14T19:10:53","slug":"hempv","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/es\/hempv\/","title":{"rendered":"Criterios Diagn\u00f3stico para Policitemia Vera (PV)"},"content":{"rendered":"<div class=\"7ca9444b8380138fe077da07353677a4\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p><\/p>\n<div class=\"Section1\">\n<p style=\"font-weight: 400;\"><strong>Criterios PVSG (Polycythemia Vera Study Group)<\/strong><\/p>\n<p style=\"font-weight: 400;\">A1 Incremento de la masa de gl\u00f3bulos rojos, hombres\u00a0<u>&gt;<\/u>\u00a036 ml\/kg, mujeres\u00a0<u>&gt;<\/u>\u00a032 ml\/kg<br \/>\nA2 Saturaci\u00f3n arterial de ox\u00edgeno normal &gt; 92%<br \/>\nA3 Esplenomegalia<\/p>\n<p><!--more--><\/p>\n<p style=\"font-weight: 400;\">B1 Recuento de plaquetas &gt; 400 x 109\/l<br \/>\nB2 Recuento de gl\u00f3bulos blancos &gt; 12 x 109\/l<br \/>\nB3 Fosfata alcalina leucocitaria &gt; 100<br \/>\nB4 Vitamina B12 s\u00e9rica &gt; 900 pg\/ml o capacidad s\u00e9rica de uni\u00f3n a la vitamina &gt; 220 pg\/ml<\/p>\n<p style=\"font-weight: 400;\"><strong>Diagn\u00f3stico<\/strong><\/p>\n<p style=\"font-weight: 400;\">A1 + A2 + A3 establece PV<br \/>\nA1 + A2 + dos de la categor\u00eda B establece PV<\/p>\n<p style=\"font-weight: 400;\"><strong>Criterios BCSH (British Committee for Standards in Haematology)<\/strong><\/p>\n<p style=\"font-weight: 400;\">A1 Incremento en la masa de gl\u00f3bulos rojos o hematocrito (HCT)\u00a0<u>&gt;<\/u>\u00a00.60 (hombres),\u00a0<u>&gt;<\/u>\u00a00.56 (mujeres)<br \/>\nA2 No eritrocitosis secundaria<br \/>\nA3 Bazo palpable<br \/>\nA4 Cariotipo anormal<\/p>\n<p style=\"font-weight: 400;\">B1 Recuento de plaquetas &gt; 400 x 109\/l<br \/>\nB2 Recuento de neutr\u00f3filos &gt; 10 x 109\/l<br \/>\nB3 Esplenomegalia en im\u00e1genes por ultrasonido<br \/>\nB4 Baja EPO s\u00e9rica o crecimiento caracter\u00edstico por unidades formadoras de progenitores &#8211; eritroides (BFU-E)<\/p>\n<p style=\"font-weight: 400;\"><strong>Diagn\u00f3stico<\/strong><\/p>\n<p style=\"font-weight: 400;\">A1 + A2 + A3 o A4 establece PV<br \/>\nA1 + A2 + dos de B establece PV<\/p>\n<p style=\"font-weight: 400;\"><strong>Criterios OMS (Organizaci\u00f3n Mundial de la Salud)<\/strong><\/p>\n<p style=\"font-weight: 400;\">A1 Incremento de la masa de gl\u00f3bulos rojos o hemoglobina (Hb) &gt; 18.5 (hombres), &gt; 16.5 (mujeres)<br \/>\nA2 No eritrocitosis secundaria<br \/>\nA3 Esplenomegalia<br \/>\nA4 Cariotipo anormal (otro que el cromosoma Ph o gen de fusi\u00f3n BCR\/ABL en c\u00e9lulas de m\u00e9dula \u00f3sea)<br \/>\nA5 Formaci\u00f3n de colonias eritroides end\u00f3genas (EEC)<\/p>\n<p style=\"font-weight: 400;\">B1 Recuento de plaquetas &gt; 400 x 109\/l<br \/>\nB2 Recuento de gl\u00f3bulos blancos &gt; 12 x 109\/l<br \/>\nB3 Biopsia de m\u00e9dula \u00f3sea (BMB) mostrando panmielosis con proliferaci\u00f3n eritroide y megacarioc\u00edtico<br \/>\nB4 Baja eritropoyetina (EPO) s\u00e9rica<\/p>\n<p style=\"font-weight: 400;\"><strong>Diagnostico<\/strong><\/p>\n<p style=\"font-weight: 400;\">A1 + A2 y cualquier otro de la categor\u00eda A establece PV<br \/>\nA1 + A2 + dos de la categor\u00eda B establece PV<\/p>\n<p>&nbsp;<\/p>\n<p style=\"font-weight: 400;\"><strong>Bibliograf\u00eda:<\/strong><\/p>\n<ol style=\"font-weight: 400;\">\n<li>Turkington RC, Arnold EC, Percy MJ, Ranaghan LA, Cuthbert RJ, McMullin MF. Comparison of diagnostic criteria for polycythaemia vera. Hematology. 2007 Apr;12(2):123-30.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17454193\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<li>Tefferi A, Thiele J, Orazi A, Kvasnicka HM, Barbui T, Hanson CA, Barosi G, Verstovsek S, Birgegard G, Mesa R, Reilly JT, Gisslinger H, Vannucchi AM, Cervantes F, Finazzi G, Hoffman R, Gilliland DG, Bloomfield CD, Vardiman JW. Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel. Blood. 2007 Aug 15;110(4):1092-7.<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17488875\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<li>Pearson TC, Messinezy M. The diagnostic criteria of polycythaemia rubra vera. Leuk Lymphoma. 1996 Sep;22 Suppl 1:87-93.<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8951778\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<li>Berlin NI. Diagnosis and classification of the polycythemias.\u00a0Semin Hematol 1975;12(4):339\u2013351.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p style=\"font-weight: 400;\">Creado: Sep 10, 2007<\/p>\n<\/div>\n<p><\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Criterios PVSG (Polycythemia Vera Study Group) A1 Incremento de la masa de gl\u00f3bulos rojos, hombres\u00a0&gt;\u00a036 ml\/kg, mujeres\u00a0&gt;\u00a032 ml\/kg A2 Saturaci\u00f3n arterial de ox\u00edgeno normal &gt; 92% A3 Esplenomegalia<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[171],"tags":[16,15,14,13,1381,1610,1609,1608,1611],"class_list":["post-2526","post","type-post","status-publish","format-standard","hentry","category-hematology","tag-criteria","tag-criterios","tag-diagnostic","tag-diagnostico","tag-hematology","tag-policitemia","tag-polycythemia","tag-pv","tag-vera"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/2526","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/comments?post=2526"}],"version-history":[{"count":3,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/2526\/revisions"}],"predecessor-version":[{"id":8829,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/2526\/revisions\/8829"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/media?parent=2526"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/categories?post=2526"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/tags?post=2526"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}