{"id":2566,"date":"2009-02-28T20:18:02","date_gmt":"2009-02-28T20:18:02","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/gasfhf\/"},"modified":"2025-05-14T19:11:52","modified_gmt":"2025-05-14T19:11:52","slug":"gasfhf","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/es\/gasfhf\/","title":{"rendered":"Criterios del King\u00b4s College Hospital para Trasplante de H\u00edgado en Insuficiencia Hep\u00e1tica Fulminante"},"content":{"rendered":"<div class=\"7ca9444b8380138fe077da07353677a4\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>En la insuficiencia hep\u00e1tica fulminante inducida por acetaminofeno, la supervivencia se correlacion\u00f3 con el pH de la sangre arterial, el tiempo m\u00e1ximo de protrombina y la creatinina s\u00e9rica: un pH inferior a 7,30, un tiempo de protrombina superior a 100 s y creatinina superior a 300 mumol\/L, lo que indica un mal pron\u00f3stico.<!--more--><\/p>\n<p style=\"font-weight: 400;\"><strong>Enfermedad inducida por acetaminofeno<\/strong><\/p>\n<p style=\"font-weight: 400;\">pH arterial &lt;7,3 (independiente del grado de encefalopat\u00eda)<\/p>\n<p style=\"font-weight: 400;\"><strong>o<\/strong><\/p>\n<ul>\n<li style=\"font-weight: 400;\">Encefalopat\u00eda grado III o IV,\u00a0<strong>y<br \/>\n<\/strong><\/li>\n<li style=\"font-weight: 400;\">Tiempo de protrombina &gt;100 segundos,\u00a0<strong>y<br \/>\n<\/strong><\/li>\n<li style=\"font-weight: 400;\">Creatinina s\u00e9rica &gt;3,4 mg\/dl (301 \u03bcmol\/L)<\/li>\n<\/ul>\n<p style=\"font-weight: 400;\"><strong>Todas las otras causas de fallo hep\u00e1tico fulminante<\/strong><\/p>\n<p style=\"font-weight: 400;\">Tiempo de protrombina &gt;100 segundos (independiente del grado de encefalopat\u00eda)<br \/>\n<strong>o<br \/>\n<\/strong>Cualquiera tres de las siguientes variables (independiente del grado de encefalopat\u00eda)<\/p>\n<ol style=\"font-weight: 400;\">\n<li>Edad &lt;10 a\u00f1os o &gt;40 a\u00f1os<\/li>\n<li>Etiolog\u00eda: hepatitis no A no B, hepatitis por halotano, reacciones idiosincr\u00e1tica a drogas<\/li>\n<li>Duraci\u00f3n de la ictericia antes del comienzo de la encefalopat\u00eda &gt;7 d\u00edas<\/li>\n<li>Tiempo de protrombina &gt;50 segundos<\/li>\n<li>Bilirrubina s\u00e9rica &gt;18 mg\/dl (308 \u03bcmol\/L)<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><strong>Bibliograf\u00eda:<\/strong><\/p>\n<ol>\n<li>O&#8217;Grady JG, Alexander GJ, Hayllar KM, Williams R. Early indicators of prognosis in fulminant hepatic failure. Gastroenterology. 1989 Aug;97(2):439-45.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2490426\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Creado: Ene 29, 2008<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>En la insuficiencia hep\u00e1tica fulminante inducida por acetaminofeno, la supervivencia se correlacion\u00f3 con el pH de la sangre arterial, el tiempo m\u00e1ximo de protrombina y la creatinina s\u00e9rica: un pH inferior a 7,30, un tiempo de protrombina superior a 100 s y creatinina superior a 300 mumol\/L, lo que indica un mal pron\u00f3stico.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[53],"tags":[1011,16,15,674,901,1729,1728,1413,648,529,1725,1427,1727,524,1724,1726],"class_list":["post-2566","post","type-post","status-publish","format-standard","hentry","category-gastroenterology","tag-college","tag-criteria","tag-criterios","tag-failure","tag-fallo","tag-fulminant","tag-fulminante","tag-gastroenterology","tag-hepatic","tag-hepatico","tag-higado","tag-hospital","tag-king","tag-liver","tag-transplantation","tag-transplante"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/2566","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/comments?post=2566"}],"version-history":[{"count":4,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/2566\/revisions"}],"predecessor-version":[{"id":8947,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/2566\/revisions\/8947"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/media?parent=2566"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/categories?post=2566"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/tags?post=2566"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}