{"id":5480,"date":"2017-10-31T12:44:05","date_gmt":"2017-10-31T12:44:05","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/comparative-effectiveness-of-statin-therapy\/"},"modified":"2025-05-13T20:25:27","modified_gmt":"2025-05-13T20:25:27","slug":"comparative-effectiveness-of-statin-therapy","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/es\/comparative-effectiveness-of-statin-therapy\/","title":{"rendered":"Eficacia Comparativa del Tratamiento con Estatinas"},"content":{"rendered":"<div class=\"7ca9444b8380138fe077da07353677a4\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p><\/p>\n<p style=\"font-weight: 400;\">Los inhibidores de HMG CoA-reductasa o estatinas son claramente la clase m\u00e1s efectiva de medicamentos para reducir el colesterol LDL. Estas drogas se han asociado con un impacto beneficioso sobre la morbididad y mortalidad cardiovascular.<\/p>\n<p><!--more--><\/p>\n<p style=\"font-weight: 400;\"><strong>Eficacia Comparativa del Tratamiento con Estatinas<\/strong><\/p>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td><strong>% LDL Reduction\u00a0<\/strong><\/td>\n<td style=\"text-align: center;\">25-32%<\/td>\n<td style=\"text-align: center;\">31-39%<\/td>\n<td style=\"text-align: center;\">37-45%<\/td>\n<td style=\"text-align: center;\">48-52%<\/td>\n<td style=\"text-align: center;\">55-60%<\/td>\n<td style=\"text-align: center;\">60-63%<\/td>\n<\/tr>\n<tr>\n<td>\u00a0Lovastatina<\/td>\n<td style=\"text-align: center;\">\u00a020 mg<\/td>\n<td style=\"text-align: center;\">\u00a040 mg<\/td>\n<td style=\"text-align: center;\">\u00a080 mg<\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<\/tr>\n<tr>\n<td>\u00a0Pravastatina<\/td>\n<td style=\"text-align: center;\">\u00a020 mg<\/td>\n<td style=\"text-align: center;\">\u00a040 mg<\/td>\n<td style=\"text-align: center;\">\u00a080 mg<\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<\/tr>\n<tr>\n<td>\u00a0Simvastatina<\/td>\n<td style=\"text-align: center;\">\u00a010 mg<\/td>\n<td style=\"text-align: center;\">\u00a020 mg<\/td>\n<td style=\"text-align: center;\">\u00a040 mg<\/td>\n<td style=\"text-align: center;\">\u00a080 mg<\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<\/tr>\n<tr>\n<td>\u00a0Fluvastatina<\/td>\n<td style=\"text-align: center;\">\u00a040 mg<\/td>\n<td style=\"text-align: center;\">\u00a080 mg<\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<\/tr>\n<tr>\n<td>\u00a0Atorvastatina<\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\">\u00a010 mg<\/td>\n<td style=\"text-align: center;\">\u00a020 mg<\/td>\n<td style=\"text-align: center;\">\u00a040 mg<\/td>\n<td style=\"text-align: center;\">\u00a080 mg<\/td>\n<td style=\"text-align: center;\"><\/td>\n<\/tr>\n<tr>\n<td>\u00a0Rosuvastatina<\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\">\u00a0 \u00a05 mg<\/td>\n<td style=\"text-align: center;\">\u00a010 mg<\/td>\n<td style=\"text-align: center;\">\u00a020 mg<\/td>\n<td style=\"text-align: center;\">\u00a040 mg<\/td>\n<\/tr>\n<tr>\n<td>\u00a0Ezetimibe\/Simvastatina<\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\"><\/td>\n<td style=\"text-align: center;\">\u00a010\/10<\/td>\n<td style=\"text-align: center;\">\u00a010\/20<\/td>\n<td style=\"text-align: center;\">\u00a010\/40<\/td>\n<td style=\"text-align: center;\">\u00a010\/80<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p style=\"font-weight: 400;\"><strong>Bibliograf\u00eda:<\/strong><\/p>\n<ol style=\"font-weight: 400;\">\n<li>Cholesterol Treatment Trialists&#8217; (CTT) Collaboration, Fulcher J, O&#8217;Connell R, Voysey M, Emberson J, Blackwell L, Mihaylova B, Simes J, Collins R, Kirby A, Colhoun H, Braunwald E, La Rosa J, Pedersen TR, Tonkin A, Davis B, Sleight P, Franzosi MG, Baigent C, Keech A. Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials.\u00a0Lancet. 2015 Apr 11;385(9976):1397-405\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25579834\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<li>Weng TC, Yang YH, Lin SJ, Tai SH. A systematic review and meta-analysis on the therapeutic equivalence of statins.\u00a0J Clin Pharm Ther. 2010 Apr;35(2):139-51.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20456733\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<li>Nicholls SJ, Brandrup-Wognsen G, Palmer M, Barter PJ. Meta-analysis of comparative efficacy of increasing dose of Atorvastatin versus Rosuvastatin versus Simvastatin on lowering levels of atherogenic lipids (from VOYAGER).\u00a0Am J Cardiol. 2010 Jan 1;105(1):69-76.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20102893\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p style=\"font-weight: 400;\">Creado Oct 31, 2017.<\/p>\n<p><\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Los inhibidores de HMG CoA-reductasa o estatinas son claramente la clase m\u00e1s efectiva de medicamentos para reducir el colesterol LDL. Estas drogas se han asociado con un impacto beneficioso sobre la morbididad y mortalidad cardiovascular.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[26],"tags":[559,560,561,562,563,564,565,566,558,557,556,548,549,550,551,552,553,554,555,567],"class_list":["post-5480","post","type-post","status-publish","format-standard","hentry","category-cardiology","tag-atorvastatin","tag-atorvastatina","tag-comparativa","tag-comparative","tag-effectiveness","tag-eficacia","tag-estatinas","tag-ezetimibe","tag-fluvastatin","tag-fluvastatina","tag-lovastatin","tag-lovastatina","tag-pravastatin","tag-pravastatina","tag-rosuvastatin","tag-rosuvastatina","tag-simvastatin","tag-simvastatina","tag-statin","tag-therapy"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/5480","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/comments?post=5480"}],"version-history":[{"count":3,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/5480\/revisions"}],"predecessor-version":[{"id":9239,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/5480\/revisions\/9239"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/media?parent=5480"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/categories?post=5480"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/tags?post=5480"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}