{"id":5815,"date":"2019-12-12T00:49:27","date_gmt":"2019-12-12T00:49:27","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/?p=5815"},"modified":"2026-01-28T18:54:48","modified_gmt":"2026-01-28T18:54:48","slug":"allred","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/es\/allred\/","title":{"rendered":"Puntuaci\u00f3n Allred para la Evaluaci\u00f3n de Receptores de Estr\u00f3genos y Progesterona"},"content":{"rendered":"<div class=\"7ca9444b8380138fe077da07353677a4\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p><\/p>\n<p style=\"font-weight: 300;\">El estado de los receptores hormonales de c\u00e1ncer de mama se eval\u00faa mediante inmunohistoqu\u00edmica (IHC), un m\u00e9todo espec\u00edfico, sensible y accesible que gu\u00eda el tratamiento del c\u00e1ncer de mama.<!--more--><br \/>\n<b><\/b><\/p>\n<p style=\"font-weight: 300;\"><b><strong style=\"font-style: inherit;\">Informe de los resultados de la prueba del receptor de estr\u00f3genos y de progesterona<\/strong><\/b><\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 111px;\" border=\"1\">\n<tbody style=\"font-style: inherit; font-weight: inherit;\">\n<tr style=\"font-style: inherit; font-weight: inherit;\">\n<td style=\"font-style: inherit; width: 12.6712%; height: 10px;\">\n<p style=\"font-style: inherit; font-weight: inherit;\"><strong>Resultado<\/strong><\/p>\n<\/td>\n<td style=\"font-style: inherit; width: 22.2603%; height: 10px;\">\n<p style=\"font-style: inherit; font-weight: inherit;\"><strong>Criterios<\/strong><\/p>\n<\/td>\n<td style=\"font-style: inherit; width: 65.0685%; height: 10px;\">\n<p style=\"font-style: inherit; font-weight: inherit;\"><strong>Comentarios<\/strong><\/p>\n<\/td>\n<\/tr>\n<tr style=\"font-style: inherit; font-weight: inherit;\">\n<td style=\"font-style: inherit; width: 12.6712%; height: 89px;\">\n<p style=\"font-style: inherit; font-weight: inherit;\">Positivo<\/p>\n<\/td>\n<td style=\"font-style: inherit; width: 22.2603%; height: 89px;\">\n<p style=\"font-style: inherit; font-weight: inherit;\">C\u00e9lulas tumorales inmunorreactivas presentes(&gt;\/=1%)<\/p>\n<\/td>\n<td style=\"font-style: inherit; width: 65.0685%; height: 89px;\">El porcentaje de c\u00e9lulas inmunorreactivas puede determinarse por estimaci\u00f3n visual o cuantificaci\u00f3n. La cuantificaci\u00f3n se puede proporcionar informando el porcentaje de c\u00e9lulas positivas o mediante un sistema de puntaje, como el score Allred o el H score.<\/td>\n<\/tr>\n<tr style=\"font-style: inherit; font-weight: inherit;\">\n<td style=\"font-style: inherit; width: 12.6712%; height: 12px;\">\n<p style=\"font-style: inherit; font-weight: inherit;\">Negativo<\/p>\n<\/td>\n<td style=\"font-style: inherit; width: 22.2603%; height: 12px;\">\n<p style=\"font-style: inherit; font-weight: inherit;\">&lt;1% C\u00e9lulas tumorales inmunorreactivas presentes<\/p>\n<\/td>\n<td style=\"font-style: inherit; width: 65.0685%; height: 12px;\">\n<p style=\"font-style: inherit; font-weight: inherit;\"><span style=\"font-style: inherit; font-weight: inherit;\">\u00a0<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><br \/>\n<ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-0127150553352455\" data-ad-slot=\"7834404329\"><\/ins><br \/>\n<script>\n     (adsbygoogle = window.adsbygoogle || []).push({});\n<\/script><\/p>\n<p style=\"font-weight: 300;\"><b><strong style=\"font-style: inherit;\">Allred score para la evaluaci\u00f3n del receptor de estr\u00f3geno y progesterona<\/strong><\/b><\/p>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 25%;\"><b><strong style=\"font-style: inherit;\"><span style=\"font-style: inherit; font-weight: inherit;\">C\u00e9lulas positivas, %<\/span><\/strong><\/b><\/td>\n<td style=\"width: 25%; text-align: center;\"><b><strong style=\"font-style: inherit;\">Proporci\u00f3n del Score<\/strong><\/b><\/td>\n<td style=\"width: 25%; text-align: center;\"><strong>Intensidad<\/strong><\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"font-style: inherit; font-weight: inherit;\"><strong>Intensidad del Score<\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%;\">0<\/td>\n<td style=\"width: 25%; text-align: center;\">0<\/td>\n<td style=\"width: 25%; text-align: center;\">Ninguna<\/td>\n<td style=\"width: 25%; text-align: center;\">0<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%;\">&lt;1<\/td>\n<td style=\"width: 25%; text-align: center;\">1<\/td>\n<td style=\"width: 25%; text-align: center;\">D\u00e9bil<\/td>\n<td style=\"width: 25%; text-align: center;\">1<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%;\">1-10<\/td>\n<td style=\"width: 25%; text-align: center;\">2<\/td>\n<td style=\"width: 25%; text-align: center;\">Intermedia<\/td>\n<td style=\"width: 25%; text-align: center;\">2<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%;\">11\u201333<\/td>\n<td style=\"width: 25%; text-align: center;\">3<\/td>\n<td style=\"width: 25%; text-align: center;\">Fuerte<\/td>\n<td style=\"width: 25%; text-align: center;\">3<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%;\">34\u201366<\/td>\n<td style=\"width: 25%; text-align: center;\">4<\/td>\n<td style=\"width: 25%;\"><\/td>\n<td style=\"width: 25%;\"><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%;\"><span style=\"font-style: inherit; font-weight: inherit;\">&gt;\/=<\/span>67<\/td>\n<td style=\"width: 25%; text-align: center;\">5<\/td>\n<td style=\"width: 25%;\"><\/td>\n<td style=\"width: 25%;\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"font-weight: 300;\">El Allred score combina el porcentaje de c\u00e9lulas positivas y la intensidad del producto de reacci\u00f3n en la mayor\u00eda del carcinoma. Los 2 puntajes se suman para obtener un puntaje final con 8 valores posibles. Las puntuaciones de 0 y 2 se consideran negativas. Las puntuaciones de 3-8 se consideran positivas.<\/p>\n<p><script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script><br \/>\n<ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-0127150553352455\" data-ad-slot=\"7834404329\"><\/ins><br \/>\n<script>\n     (adsbygoogle = window.adsbygoogle || []).push({});\n<\/script><br \/>\n<b><strong style=\"font-style: inherit;\">H score para la evaluaci\u00f3n del receptor de estr\u00f3geno y progesterona<\/strong><\/b><\/p>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\" rowspan=\"2\"><span style=\"font-style: inherit; font-weight: inherit;\">Se\u00f1al Celular<\/span><\/td>\n<td style=\"width: 33.3333%; text-align: center;\" colspan=\"2\">C\u00e1lculo de la puntuaci\u00f3n H<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%; text-align: center;\"><span style=\"font-style: inherit; font-weight: inherit;\">Porcentaje de C\u00e9lulas<\/span><\/td>\n<td style=\"width: 33.3333%; text-align: center;\">Valor multiplicado<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">C\u00e9lulas\u00a0sin se\u00f1al<\/td>\n<td style=\"width: 33.3333%; text-align: center;\">%<\/td>\n<td style=\"width: 33.3333%; text-align: center;\"><span style=\"font-style: inherit; font-weight: inherit;\">x0=<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\"><span style=\"font-style: inherit; font-weight: inherit;\">C\u00e9lulas<\/span>\u00a0con se\u00f1al d\u00e9bil<\/td>\n<td style=\"width: 33.3333%; text-align: center;\">%<\/td>\n<td style=\"width: 33.3333%; text-align: center;\">x1=<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\"><span style=\"font-style: inherit; font-weight: inherit;\">C\u00e9lulas<\/span>\u00a0con se\u00f1al moderada<\/td>\n<td style=\"width: 33.3333%; text-align: center;\">%<\/td>\n<td style=\"width: 33.3333%; text-align: center;\"><span style=\"font-style: inherit; font-weight: inherit;\">x2=<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\"><span style=\"font-style: inherit; font-weight: inherit;\">C\u00e9lulas<\/span>\u00a0con se\u00f1al fuerte<\/td>\n<td style=\"width: 33.3333%; text-align: center;\">%<\/td>\n<td style=\"width: 33.3333%; text-align: center;\"><span style=\"font-style: inherit; font-weight: inherit;\">x3=<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Total del score =<\/td>\n<td style=\"width: 33.3333%;\"><\/td>\n<td style=\"width: 33.3333%;\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"font-weight: 300;\">La puntuaci\u00f3n H se determina multiplicando el porcentaje de c\u00e9lulas que demuestran cada intensidad (puntuado de 0 a 3) y agregando los resultados. Hay 300 valores posibles. En este sistema, &lt;1% de c\u00e9lulas positivas se considera un resultado negativo.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Bibliograf\u00eda:<\/strong><\/p>\n<ol style=\"font-weight: 300;\">\n<li style=\"font-style: inherit; font-weight: inherit;\">Fitzgibbons PL, Dillon DA, Alsabeh R, Berman MA, Hayes DF, Hicks DG, Hughes KS, Nofech-Mozes S.\u00a0Template for reporting results of biomarker testing of specimens from patients with carcinoma of the breast.\u00a0Arch Pathol Lab Med. 2014 May;138(5):595-601.\u00a0<a style=\"font-style: inherit; font-weight: inherit;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24236805\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li style=\"font-style: inherit; font-weight: inherit;\">Dalto\u00e9 RD, Madeira KP, de Carvalho AA, de Rezende LC, Silva IV, Rangel LB. Evaluation of the progesterone receptor status in breast cancer using three different antibodies: a comparison by Allred score system.\u00a0Int J Clin Exp Pathol. 2013 Dec 15;7(1):331-9.\u00a0<a style=\"font-style: inherit; font-weight: inherit;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24427354\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li style=\"font-style: inherit; font-weight: inherit;\">Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, Fitzgibbons PL, Francis G, Goldstein NS, Hayes M, Hicks DG, Lester S, Love R, Mangu PB, McShane L, Miller K, Osborne CK, Paik S, Perlmutter J, Rhodes A, Sasano H, Schwartz JN, Sweep FC, Taube S, Torlakovic EE, Valenstein P, Viale G, Visscher D, Wheeler T, Williams RB, Wittliff JL, Wolff AC; American Society of Clinical Oncology; College of American Pathologists. American Society of Clinical Oncology\/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version). Arch Pathol Lab Med. 2010 Jul;134(7):e48-72.\u00a0<a style=\"font-style: inherit; font-weight: inherit;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20586616\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Ogawa A, Murata T, Yoshida M, Ohgi N, Hashiguchi H, Nakashoji A, Maeda H, Watase C, Iwamoto E, Takayama S. Evaluation of progesterone receptors with different cutoff values according to menopausal status in hormone-positive early breast cancer. Sci Rep. 2025 Nov 14;15(1):40023. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41238736\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Creado Feb 06, 2018.<br \/>\nActualizado Ene 28, 2026.<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>El estado de los receptores hormonales de c\u00e1ncer de mama se eval\u00faa mediante inmunohistoqu\u00edmica (IHC), un m\u00e9todo espec\u00edfico, sensible y accesible que gu\u00eda el tratamiento del c\u00e1ncer de mama.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[2082],"tags":[2077,2080,2078,161,160,2079,2081,445,597,596,450],"class_list":["post-5815","post","type-post","status-publish","format-standard","hentry","category-pathologic","tag-allred","tag-estrogen","tag-estrogenos","tag-evaluacion","tag-evaluation","tag-progesterona","tag-progesterone","tag-puntuacion","tag-receptor","tag-receptores","tag-score"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/5815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/comments?post=5815"}],"version-history":[{"count":10,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/5815\/revisions"}],"predecessor-version":[{"id":10598,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/5815\/revisions\/10598"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/media?parent=5815"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/categories?post=5815"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/tags?post=5815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}