{"id":7429,"date":"2020-03-06T21:52:37","date_gmt":"2020-03-06T21:52:37","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/?p=7429"},"modified":"2026-01-09T19:08:39","modified_gmt":"2026-01-09T19:08:39","slug":"clinical-coronavirus","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/es\/clinical-coronavirus\/","title":{"rendered":"Caracter\u00edsticas Cl\u00ednicas de la Enfermedad por Coronavirus (Covid-19)"},"content":{"rendered":"<div class=\"7ca9444b8380138fe077da07353677a4\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>Durante la fase inicial del brote de Covid-19, el diagn\u00f3stico de la enfermedad se complic\u00f3 por la diversidad de s\u00edntomas y hallazgos de im\u00e1genes y por la gravedad de la enfermedad en el momento de la presentaci\u00f3n.<!--more--><\/p>\n<p>El Covid-19 se propag\u00f3 r\u00e1pidamente por toda China y caus\u00f3 diversos grados de enfermedad. Los pacientes a menudo se presentaron sin fiebre, y muchos no ten\u00edan hallazgos radiol\u00f3gicos anormales.<\/p>\n<p><strong>Caracter\u00edsticas Cl\u00ednicas de la Enfermedad por Coronavirus en China<\/strong><\/p>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\"><strong>Caracter\u00edstica<\/strong><\/td>\n<td style=\"width: 32.7054%; height: 24px;\"><\/td>\n<\/tr>\n<tr style=\"height: 192px;\">\n<td style=\"width: 67.2946%; height: 192px;\">Edad<br \/>\n* Media (a\u00f1os)<br \/>\n* Distribuci\u00f3n<br \/>\n&#8211; 0-14 a\u00f1os<br \/>\n&#8211; 15-49 a\u00f1os<br \/>\n&#8211; 50-64 a\u00f1os<br \/>\n&#8211; \u226565 a\u00f1os<\/td>\n<td style=\"width: 32.7054%; height: 192px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n47 (35-58)<br \/>\n<span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n0.9<br \/>\n55.1<br \/>\n28.9<br \/>\n15.1<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Sexo Femenino (%)<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\">41.9<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Historia de tabaquismo (%)<br \/>\n* Nunca fum\u00f3<br \/>\n* Ex fumador<br \/>\n* Fumador actual<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n85.4<br \/>\n1.9<br \/>\n12.6<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Per\u00edodo medio de incubaci\u00f3n (d\u00edas)<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\">4 (2-7)<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Fiebre en la admisi\u00f3n<br \/>\n* Pacientes (%)<br \/>\n* Temperatura Media<br \/>\n* Distribuci\u00f3n de la temperatura (%)<br \/>\n&#8211; &lt;37.5\u202f\u00b0C<br \/>\n&#8211; 37.5-38.0\u202f\u00b0C<br \/>\n&#8211; 38.1-39.0\u202f\u00b0C<br \/>\n&#8211; &gt;39.0\u202f\u00b0C<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n43.8<br \/>\n37.3 (36.7-38.0)<br \/>\n<span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n9.9<br \/>\n30.9<br \/>\n46.9<br \/>\n12.3<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Fiebre durante la hospitalizaci\u00f3n<br \/>\n* Pacientes (%)<br \/>\n* Temperatura media m\u00e1s elevada (\u00b0C)<br \/>\n&#8211; &lt;37.5\u202f\u00b0C<br \/>\n&#8211; 37.5-38.0\u202f\u00b0C<br \/>\n&#8211; 38.1-39.0\u202f\u00b0C<br \/>\n&#8211; &gt;39.0\u202f\u00b0C<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n88.7<br \/>\n38.3 (37.8-38.9)<br \/>\n9.9<br \/>\n30.9<br \/>\n46.9<br \/>\n12.3<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">S\u00edntomas (%)<br \/>\n* Congesti\u00f3n conjuntival<br \/>\n* Congesti\u00f3n nasal<br \/>\n* Cefalea<br \/>\n* Tos<br \/>\n* Dolor de garganta<br \/>\n* Producci\u00f3n de esputo<br \/>\n* Fatiga<br \/>\n* Hemoptisis<br \/>\n* Respiraci\u00f3n entrecortada<br \/>\n* N\u00e1usea o v\u00f3mitos<br \/>\n* Diarrea<br \/>\n* Mialgias o artralgias<br \/>\n* Escalofr\u00edos<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n0.3<br \/>\n4.8<br \/>\n13.6<br \/>\n67.8<br \/>\n13.9<br \/>\n33.7<br \/>\n38.1<br \/>\n0.9<br \/>\n18.7<br \/>\n5.0<br \/>\n3.8<br \/>\n14.9<br \/>\n11.5<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Signos de infecci\u00f3n (%)<br \/>\n* Congesti\u00f3n de fauces<br \/>\n* Inflamaci\u00f3n de am\u00edgdalas<br \/>\n* Adenopat\u00edas<br \/>\n* Rash<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n1.7<br \/>\n2.1<br \/>\n0.2<br \/>\n0.2<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Enfermedades coexistentes (%)<br \/>\n* Ninguna<br \/>\n* Enfermedad pulmonar obstructiva cr\u00f3nica<br \/>\n* Diabetes<br \/>\n* Hipertensi\u00f3n<br \/>\n* Enfermedad coronaria<br \/>\n* Enfermedad cerebrovascular<br \/>\n* Hepatitis B<br \/>\n* C\u00e1ncer<br \/>\n* Enfermedad renal cr\u00f3nica<br \/>\n* Inmunodeficiencia<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n23.7<br \/>\n1.1<br \/>\n7.4<br \/>\n15.0<br \/>\n2.3<br \/>\n1.4<br \/>\n2.1<br \/>\n0.9<br \/>\n0.7<br \/>\n0.2<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\"><strong>Hallazgos radiol\u00f3gicos<\/strong><\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Anormalidades en la radiograf\u00eda de t\u00f3rax (%)<br \/>\n* Opacidad en vidrio esmerilado<br \/>\n* Infiltrado irregular local<br \/>\n* Infiltrado irregular bilateral<br \/>\n* Anormalidades Intersticiales<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\">59.1<br \/>\n20.1<br \/>\n28.1<br \/>\n36.5<br \/>\n4.4<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Anormalidades en la TC de t\u00f3rax (%)<br \/>\n* Opacidad en vidrio esmerilado<br \/>\n* Infiltrado irregular local<br \/>\n* Infiltrado irregular bilateral<br \/>\n* Anormalidades Intersticiales<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\">86.2<br \/>\n56.4<br \/>\n41.9<br \/>\n51.8<br \/>\n14.7<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\"><strong>Hallazgos de laboratorio<\/strong><\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Relaci\u00f3n media Pao2:Fio2<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\">3.9 (2.9-4.7)<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Recuento de gl\u00f3bulos blancos<br \/>\n* Media (por mm3)<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n4700 (3500-6000)<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Distribuci\u00f3n (%)<br \/>\n* &gt;10,000 por mm3<br \/>\n* &lt;4000 por mm3<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n5.9<br \/>\n33.7<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Recuento de linfocitos<br \/>\n* Media (por mm3)<br \/>\n* Distribuci\u00f3n (%)<br \/>\n&#8211; &lt;1500 por mm3<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n1000 \/(700-1300)<br \/>\n<span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n83.2<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Distribuci\u00f3n de otros hallazgos (%)<br \/>\n* Prote\u00edna C-reactiva \u226510 mg\/litro<br \/>\n* Procalcitonina \u22650.5 ng\/ml<br \/>\n* Lactato deshidrogenasa \u2265250 U\/litro<br \/>\n* Aspartato aminotransferasa (GOT) &gt;40 U\/litro<br \/>\n* Alanina aminotransferasa (GPT) &gt;40 U\/litro<br \/>\n* Bilirubina total &gt;17.1 \u03bcmol\/litro<br \/>\n* Creatina kinasa \u2265200 U\/litro<br \/>\n* Creatinina \u2265133 \u03bcmol\/litro<br \/>\n* D\u00edmero D \u22650.5 mg\/litro<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n60.7<br \/>\n5.5<br \/>\n41.0<br \/>\n22.2<br \/>\n21.3<br \/>\n10.5<br \/>\n13.7<br \/>\n1.6<br \/>\n46.4<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\"><strong>Complicaciones<\/strong><\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Shock s\u00e9ptico (%)<br \/>\nS\u00edndrome de distr\u00e9s respiratorio agudo (%)<br \/>\nInjuria renal aguda (%)<br \/>\nCoagulaci\u00f3n intravascular diseminada (%)<br \/>\nRabdomi\u00f3lisis (%)<br \/>\nNeumon\u00eda\u00a0diagnosticada por los m\u00e9dicos (%)<br \/>\nTiempo medio hasta el desarrollo de la neumon\u00eda (d\u00edas)<br \/>\n* Despu\u00e9s del diagn\u00f3stico inicial de Covid-19<br \/>\n* Despu\u00e9s del inicio de los s\u00edntomas de Covid-19<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\">1.1<br \/>\n3.4<br \/>\n0.5<br \/>\n0.1<br \/>\n0.2<br \/>\n91.1<br \/>\n<span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n0 (0-1)<br \/>\n3 (1-6)<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 67.2946%; height: 24px;\">Resultados cl\u00ednicos en el corte de datos (%)<br \/>\n* Alta hospitalaria<br \/>\n* Muerte<br \/>\n* Recuperaci\u00f3n<br \/>\n* Hospitalizaci\u00f3n<\/td>\n<td style=\"width: 32.7054%; height: 24px; text-align: center;\"><span style=\"color: #ffffff;\">&#8211;<\/span><br \/>\n5.0<br \/>\n1.4<br \/>\n0.8<br \/>\n93.6<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p><strong>Bibliograf\u00eda:<\/strong><\/p>\n<ol>\n<li>Guan WJ, Ni ZY, Hu Y, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020;10.1056\/NEJMoa2002032. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32109013\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Xu XW, Wu XX, Jiang XG, et al. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series. BMJ. 2020;368:m606. Published 2020 Feb 19. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32075786\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Yang W, Cao Q, Qin L, et al. Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19):A multi-center study in Wenzhou city, Zhejiang, China. J Infect. 2020;S0163-4453(20)30099-2. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32112884\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Creado Mar 06, 2020.<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Durante la fase inicial del brote de Covid-19, el diagn\u00f3stico de la enfermedad se complic\u00f3 por la diversidad de s\u00edntomas y hallazgos de im\u00e1genes y por la gravedad de la enfermedad en el momento de la presentaci\u00f3n.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[39],"tags":[40,952,490,935,2123,2146,51,50],"class_list":["post-7429","post","type-post","status-publish","format-standard","hentry","category-infetious-disease","tag-caracteristicas","tag-characteristics","tag-clinical","tag-clinicas","tag-coronavirus","tag-covid-19","tag-disease","tag-enfermedad"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/7429","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/comments?post=7429"}],"version-history":[{"count":10,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/7429\/revisions"}],"predecessor-version":[{"id":9172,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/posts\/7429\/revisions\/9172"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/media?parent=7429"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/categories?post=7429"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/es\/wp-json\/wp\/v2\/tags?post=7429"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}