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EULAR/ACR New Classification Criteria for Systemic Lupus Erythematosus (SLE)

The new EULAR/ACR classification criteria use anti-nuclear antibodies (ANA) as an entry criterion. (Non-infectious) fever is the one new criterion. All criteria items now have individual weights (from 2 to 10) and are structured in domains, within which only the highest item is counted. There is one common attribution rule, counting criteria only if there is no more likely alternative explanation. Ten points are sufficient for classification. The new criteria have reached a sensitivity of 96.1% and a specificity of 93.4%. Continue reading “EULAR/ACR New Classification Criteria for Systemic Lupus Erythematosus (SLE)”

Classification Criteria for the Diagnosis of Systemic Lupus Erythematosus (SLE)

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown cause that can affect virtually any organ of the body. Immunologic abnormalities, especially the production of a number of antinuclear antibodies (ANA), are a prominent feature of the disease. Continue reading “Classification Criteria for the Diagnosis of Systemic Lupus Erythematosus (SLE)”

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