The new EULAR/ACR classification criteria use anti-nuclear antibodies (ANA) as an entry criterion. (Non-infectious) fever is the one new criterion. All criteria items now have individual weights (from 2 to 10) and are structured in domains, within which only the highest item is counted. There is one common attribution rule, counting criteria only if there is no more likely alternative explanation. Ten points are sufficient for classification. The new criteria have reached a sensitivity of 96.1% and a specificity of 93.4%.
Systemic
Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)
Disease activity is assessed using a combination of the clinical history, physical examination, organ specific functional tests, and serologic studies.
Criteria for the Classification of Systemic Sclerosis (Scleroderma)
1980 Criteria for the Classification of Systemic Sclerosis
The American College of Rheumatology (former American Rheumatism Association – ARA) has defined criteria, that are 97 % sensitive and 98 % specific for systemic sclerosis (SSc) as follows:
Major criterion:
- Proximal diffuse (truncal) sclerosis (skin tightness, thickening, non-pitting induration)
Diagnostic Criteria for Systemic Mastocytosis (SM)
If at least 1 major and 1 one minor, or at least 3 minor criteria, are met, the diagnosis of Systemic Mastocytosis (SM) can be established.
Classification Criteria for the Diagnosis of Systemic Lupus Erythematosus (SLE)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown cause that can affect virtually any organ of the body. Immunologic abnormalities, especially the production of a number of antinuclear antibodies (ANA), are a prominent feature of the disease.
Relative Potencies of Systemic Glucocorticoids
Glucocorticosteroids are a product of the adrenal cortex and perform a staggering number of physiological effects essential for life. Their clinical use is largely predicated on their anti-inflammatory and immunosuppressive properties.