Disease activity is assessed using a combination of the clinical history, physical examination, organ specific functional tests, and serologic studies.
Continue reading “Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)”
Disease activity is assessed using a combination of the clinical history, physical examination, organ specific functional tests, and serologic studies.
Continue reading “Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)”
1980 Criteria for the Classification of Systemic Sclerosis
The American College of Rheumatology (former American Rheumatism Association – ARA) has defined criteria, that are 97 % sensitive and 98 % specific for systemic sclerosis (SSc) as follows:
Major criterion:
Proximal diffuse (truncal) sclerosis (skin tightness, thickening, non-pitting induration)
Continue reading “Criteria for the Classification of Systemic Sclerosis (Scleroderma)”
If at least 1 major and 1 one minor, or at least 3 minor criteria, are met, the diagnosis of Systemic Mastocytosis (SM) can be established.
Continue reading “Diagnostic Criteria for Systemic Mastocytosis (SM)”
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown cause that can affect virtually any organ of the body. Immunologic abnormalities, especially the production of a number of antinuclear antibodies (ANA), are a prominent feature of the disease. Continue reading “Classification Criteria for the Diagnosis of Systemic Lupus Erythematosus (SLE)”
Glucocorticosteroids are a product of the adrenal cortex and perform a staggering number of physiological effects essential for life. Their clinical use is largely predicated on their anti-inflammatory and immunosuppressive properties.
Continue reading “Relative Potencies of Systemic Glucocorticoids”
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