{"id":10,"date":"2009-02-18T18:50:16","date_gmt":"2009-02-18T18:50:16","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/hemanemia\/"},"modified":"2025-05-14T21:05:54","modified_gmt":"2025-05-14T21:05:54","slug":"hemanemia","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/hemanemia\/","title":{"rendered":"Serum Levels That Differentiate Anemia of Chronic Disease from Iron-Deficiency Anemia"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>Iron deficiency anemia develops when body stores of iron drop too low to support normal red blood cell (RBC) production. Inadequate dietary iron, impaired iron absorption, bleeding, or loss of body iron in the urine may be the cause.<\/p>\n<p><!--more--><\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 192px;\" border=\"1\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\"><strong>Variable<\/strong><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><strong><span style=\"text-align: center;\">Anemia of Chronic Disease<\/span><\/strong><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><strong><span class=\"SpellE\" style=\"text-align: center;\">Iron<\/span><span style=\"text-align: center;\">&#8211;<\/span><span class=\"SpellE\" style=\"text-align: center;\">Deficiency<\/span><span style=\"text-align: center;\">\u00a0Anemia<\/span><\/strong><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><strong><span style=\"text-align: center;\">Both Conditions<\/span><\/strong><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Iron<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Trasnferrin<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced to normal<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Increased<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Transferrin saturation<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Ferritin<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Normal to increased<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Reduced to normal<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Soluble transferrin receptor<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Normal<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Increased<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Normal to increased<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Ratio of soluble transferrin receptor to log ferritin<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Low (&lt;1)<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">High (&gt;2)<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">High (&gt;2)<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Cytokine Levels<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Increased<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Normal<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: center;\">Increased<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p class=\"MsoNormal\">Patients with both conditions include those with anemia of chronic disease and true iron deficiency.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>References:<\/strong><\/p>\n<ol style=\"margin-top: 0cm;\">\n<li class=\"MsoNormal\">Weiss G, <span class=\"SpellE\">Goodnough<\/span> LT. <span class=\"SpellE\">Anemia<\/span> of chronic disease. N <span class=\"SpellE\">Engl<\/span> J Med. 2005 Mar 10<span class=\"GramE\">;352<\/span>(10):1011-23. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15758012\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p class=\"MsoNormal\">Created: May 03, 2005<\/p>\n<p class=\"MsoNormal\">\n<p><\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[171],"tags":[370,146,145,162,1016,1944,51,1173,1381,1172,1174,1023,1022,1943,1942,1945],"class_list":["post-10","post","type-post","status-publish","format-standard","hentry","category-hematology","tag-anemia","tag-chronic","tag-cronica","tag-deficiency","tag-deficit","tag-differentiate","tag-disease","tag-ferropenica","tag-hematology","tag-hierro","tag-iron","tag-levels","tag-niveles","tag-serico","tag-serum","tag-suero"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/10","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/comments?post=10"}],"version-history":[{"count":2,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/10\/revisions"}],"predecessor-version":[{"id":9032,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/10\/revisions\/9032"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/media?parent=10"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/categories?post=10"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/tags?post=10"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}