{"id":10316,"date":"2024-04-10T20:42:22","date_gmt":"2024-04-10T20:42:22","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/?p=10316"},"modified":"2025-12-30T18:56:56","modified_gmt":"2025-12-30T18:56:56","slug":"psoriasis-pasi","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/psoriasis-pasi\/","title":{"rendered":"Psoriasis Area Severity Index (PASI) Score"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>The Psoriasis Area Severity Index (PASI) is a tool used to measure the severity of psoriasis, a chronic autoimmune skin condition characterized by red, scaly patches on the skin. PASI takes into account the extent of psoriatic involvement (area) as well as the severity of erythema (redness), induration (thickness), and desquamation (scaling) present within the involved regions. It provides a quantitative assessment of psoriasis severity and is commonly used in clinical trials and practice to monitor disease progression and treatment efficacy.<!--more--><\/p>\n<p><a href=\"https:\/\/www.huidziekten.nl\/pdf\/PASI-Psoriasis-Area-and-Severity-Index.pdf\"><span style=\"font-weight: 400;\">Microsoft Word &#8211; Psoriasis Area and Severity Index _PASI_ &#8211; 01.10.12 (huidziekten.nl)<\/span><\/a><\/p>\n<p>Psoriasis Area Severity Index (PASI) Score<\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 360px;\" border=\"1\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\">Plaque characteristic<\/td>\n<td style=\"width: 16.6667%; height: 24px;\">Lesion score<\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\"><span style=\"font-weight: 400;\">Head<\/span><\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\">Upper Limbs<\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\">Trunk<\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\"><span style=\"font-weight: 400;\">Lower Limbs<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\">Erythema<\/td>\n<td style=\"width: 16.6667%; height: 72px;\" rowspan=\"3\">0 = None<br \/>\n1 = Slight<br \/>\n2 = Moderate<br \/>\n3 = Severe<br \/>\n4 = Very severe<\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\">Induration\/Thickness<\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\">Scaling<\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"6\">Add together each of the 3 scores for each body region to give 4 separate sums (A).<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"2\">Lesion Score Sum (A)<\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\">Percentage area affected<\/td>\n<td style=\"width: 16.6667%; height: 24px;\">Area score<\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\"><span style=\"font-weight: 400;\">Head<\/span><\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\">Upper Limbs<\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\">Trunk<\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\">Lower Limbs<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\">Area Score (B)<br \/>\nDegree of involvement as a percentage for each body region affected (score each region with score between 0-6)<\/td>\n<td style=\"width: 16.6667%; height: 24px;\">0 = None<br \/>\n1 = Slight<br \/>\n2 = Moderate<br \/>\n3 = Severe<br \/>\n4 = Very severe<\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"6\">Multiply Lesion Score Sum (A) by Area Score (B), for each body region, to give 4 individual subtotals (C).<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"2\">Subtotals (C)<\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"6\">Multiply each of the Subtotals (C) by amount of body surface area represented by that region, i.e. x 0.1 for head, x\u00a00.2 for upper body, x 0.3 for trunk, and x 0.4 for lower limbs.<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"2\"><span style=\"font-weight: 400;\">Body Surface Area<\/span><\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\"><span style=\"font-weight: 400;\">x 0.1<\/span><\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\"><span style=\"font-weight: 400;\">x 0.2<\/span><\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\"><span style=\"font-weight: 400;\">x 0.3<\/span><\/td>\n<td style=\"width: 16.6667%; height: 24px; text-align: center;\"><span style=\"font-weight: 400;\">x 0.4<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"2\"><span style=\"font-weight: 400;\">Totals (D)<\/span><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<td style=\"width: 16.6667%; height: 24px;\"><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"6\">Add together each of the scores for each body region to give the final PASI Score.<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"2\"><span style=\"font-weight: 400;\">PASI Score<\/span><\/td>\n<td style=\"width: 16.6667%; height: 24px;\" colspan=\"4\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>The PASI score ranges from 0 to 72, with higher scores indicating more severe psoriasis. Here&#8217;s a breakdown of the severity levels:<\/p>\n<p>PASI score &lt; 10: Mild psoriasis<br \/>\nPASI score 10-20: Moderate psoriasis<br \/>\nPASI score &gt; 20: Severe psoriasis<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">\u00a0<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><b>References:<\/b><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">El Miedany Y, El Gaafary M, Youssef S, Almedany S, Palmer D. Using Simulation in Clinical Education: Psoriasis Area and Severity Index (PASI) Score Assessment. Curr Rheumatol Rev. 2016;12(3):195-201.<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27470256\/\" target=\"_blank\" rel=\"noopener\"> <span style=\"font-weight: 400;\">[Medline]<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Manchanda Y, De A, Das S, Chakraborty D. Disease Assessment in Psoriasis. Indian J Dermatol. 2023 May-Jun;68(3):278-281.<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37529444\/\" target=\"_blank\" rel=\"noopener\"> <span style=\"font-weight: 400;\">[Medline]<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Robinson A, Kardos M, Kimball AB. Physician Global Assessment (PGA) and Psoriasis Area and Severity Index (PASI): why do both? A systematic analysis of randomized controlled trials of biologic agents for moderate to severe plaque psoriasis. J Am Acad Dermatol. 2012 Mar;66(3):369-75.<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22041254\/\" target=\"_blank\" rel=\"noopener\"> <span style=\"font-weight: 400;\">[Medline]<\/span><\/a><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Created Mar 25, 2024.<\/span><\/p>\n<p>&nbsp;<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[45],"tags":[2649,59,222,2650,1424,450,226,180],"class_list":["post-10316","post","type-post","status-publish","format-standard","hentry","category-rheumatology","tag-area","tag-index","tag-indice","tag-pasi","tag-psoriasis","tag-score","tag-severidad","tag-severity"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/10316","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/comments?post=10316"}],"version-history":[{"count":11,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/10316\/revisions"}],"predecessor-version":[{"id":10332,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/10316\/revisions\/10332"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/media?parent=10316"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/categories?post=10316"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/tags?post=10316"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}