{"id":2169,"date":"2018-12-27T21:11:18","date_gmt":"2018-12-27T21:11:18","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/?p=1475"},"modified":"2026-02-06T19:06:50","modified_gmt":"2026-02-06T19:06:50","slug":"who-hiv-infection","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/who-hiv-infection\/","title":{"rendered":"WHO Immunological Classification for Established HIV Infection"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>The revised clinical staging and immunological classification of HIV are\u00a0designed to assist in clinical management of HIV, especially where there is limited laboratory capacity.<!--more--><\/p>\n<p><strong>WHO immunological classification for established HIV infection<\/strong><\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 165px;\" border=\"1\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 17.5824%; height: 72px;\" rowspan=\"2\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">HIV-associated immunodeficiency<\/span><\/td>\n<td style=\"text-align: center; width: 82.2954%; height: 24px;\" colspan=\"4\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">Age-related CD4 values<\/span><\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"width: 20.3907%; height: 48px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&lt;11 months <\/span><br \/>\n<span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">(CD4 percent)<\/span><\/td>\n<td style=\"width: 19.9023%; height: 48px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">12 to 35 months <\/span><br \/>\n<span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">(CD4 percent)<\/span><\/td>\n<td style=\"width: 20.5128%; height: 48px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">36 to 59 months <\/span><br \/>\n<span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">(CD4 percent)<\/span><\/td>\n<td style=\"width: 21.4896%; height: 48px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&gt;5 years (absolute number per mm3 or CD4 percent)<\/span><\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"width: 17.5824%; height: 22px;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">None or not significant<\/span><\/td>\n<td style=\"width: 20.3907%; height: 22px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&gt;35<\/span><\/td>\n<td style=\"width: 19.9023%; height: 22px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&gt;30<\/span><\/td>\n<td style=\"width: 20.5128%; height: 22px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&gt;25<\/span><\/td>\n<td style=\"width: 21.4896%; height: 22px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&gt;500<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 17.5824%; height: 24px;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">Mild<\/span><\/td>\n<td style=\"width: 20.3907%; height: 24px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">30 to 35<\/span><\/td>\n<td style=\"width: 19.9023%; height: 24px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">25 to 30<\/span><\/td>\n<td style=\"width: 20.5128%; height: 24px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">20 to 25<\/span><\/td>\n<td style=\"width: 21.4896%; height: 24px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">350 to 499<\/span><\/td>\n<\/tr>\n<tr style=\"height: 23px;\">\n<td style=\"width: 17.5824%; height: 23px;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">Moderate<\/span><\/td>\n<td style=\"width: 20.3907%; height: 23px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">25 to 29<\/span><\/td>\n<td style=\"width: 19.9023%; height: 23px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">20 to 24<\/span><\/td>\n<td style=\"width: 20.5128%; height: 23px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">15 to 19<\/span><\/td>\n<td style=\"width: 21.4896%; height: 23px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">200 to 349<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 17.5824%; height: 24px;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">Severe<\/span><\/td>\n<td style=\"width: 20.3907%; height: 24px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&lt;25<\/span><\/td>\n<td style=\"width: 19.9023%; height: 24px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&lt;20<\/span><\/td>\n<td style=\"width: 20.5128%; height: 24px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&lt;15<\/span><\/td>\n<td style=\"width: 21.4896%; height: 24px; text-align: center;\"><span style=\"font-size: 8pt; font-family: arial, helvetica, sans-serif;\">&lt;200 or &lt;15 percent<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-size: 8pt;\">CD4 cells expressed as number of cells per mm<sup>3<\/sup> or percentage of total lymphocytes.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>References:<\/strong><\/p>\n<ol>\n<li>Centers for Disease Control and Prevention (CDC). Revised surveillance case definition for HIV infection&#8211;United States, 2014.\u00a0MMWR Recomm Rep. 2014 Apr 11;63(RR-03):1-10. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24717910\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>WHO case definitions of HIV for surveillance and revised clinical staging and immunological classification of HIV-related disease in adults and children. World Health Organization 2007<\/li>\n<li>Dhana A, Hamada Y, Kengne AP, Kerkhoff AD, Broger T, Denkinger CM, Rangaka MX, Gupta-Wright A, Fielding K, Wood R, Huerga H, R\u00fccker SCM, Bjerrum S, Johansen IS, Thit SS, Kyi MM, Hanson J, Barr DA, Meintjes G, Maartens G. Diagnostic accuracy of WHO screening criteria to guide lateral-flow lipoarabinomannan testing among HIV-positive inpatients: A systematic review and individual participant data meta-analysis. J Infect. 2022 Jul;85(1):40-48. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35588942\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Created: Dec 27, 2018.<br \/>\nUp-date: Feb 6, 2026.<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[39],"tags":[166,167,319,321,312,320,266,267,318,307,310,306],"class_list":["post-2169","post","type-post","status-publish","format-standard","hentry","category-infetious-disease","tag-clasificacion","tag-classification","tag-establecida","tag-established","tag-hiv","tag-immunological","tag-infeccion","tag-infection","tag-inmunologica","tag-oms","tag-vih","tag-who"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/2169","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/comments?post=2169"}],"version-history":[{"count":3,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/2169\/revisions"}],"predecessor-version":[{"id":10640,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/2169\/revisions\/10640"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/media?parent=2169"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/categories?post=2169"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/tags?post=2169"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}