{"id":2362,"date":"2014-08-18T21:31:26","date_gmt":"2014-08-18T21:31:26","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/claakd\/"},"modified":"2026-04-08T20:10:03","modified_gmt":"2026-04-08T20:10:03","slug":"claakd","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/claakd\/","title":{"rendered":"Classifications of Acute Kidney Injury and Chronic Kidney Disease"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>Recently developed consensus functional\u00a0definitions on the basis of specific changes in the serum creatinine concentration\u00a0and urine volume now complement anatomical approaches to diagnosis.<br \/>\n<!--more--><br \/>\n<strong>Classifications of Acute Kidney Injury and Chronic Kidney Disease<\/strong><\/p>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\"><strong>Stage<\/strong><\/td>\n<td colspan=\"2\" width=\"67%\"><strong>Assessments<\/strong><\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\"><strong>Acute kidney\u00a0injury<\/strong><\/td>\n<td width=\"33%\"><strong>Serum Creatinine Concentration<\/strong><\/td>\n<td width=\"33%\"><strong>Urine Output<\/strong><\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\">1<\/td>\n<td width=\"33%\">1.5\u20131.9 \u00d7 baseline or &gt;\/=0.3 mg\/dl\u00a0above baseline<\/td>\n<td width=\"33%\">&lt;0.5 ml\/kg\/hr for 6\u201312 hr<\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\">2<\/td>\n<td width=\"33%\">2.0\u20132.9 \u00d7 baseline<\/td>\n<td width=\"33%\">&lt;0.5 ml\/kg\/hr for &gt;12 hr<\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\">3<\/td>\n<td width=\"33%\">&gt;\/=3.0 \u00d7 baseline, &gt;\/=4.0 mg\/dl, or initiation of renal-replacement therapy<\/td>\n<td width=\"33%\">&lt;0.3 ml\/kg\/hr for &gt;\/=24 hr\u00a0or anuria for &gt;\/=12 hr<\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\"><strong>Chronic kidney\u00a0disease<\/strong><\/td>\n<td width=\"33%\"><strong>Definition<\/strong><\/td>\n<td width=\"33%\"><strong>GFR (ml\/min\/1.73 m2)<\/strong><\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\">1<\/td>\n<td width=\"33%\">Kidney damage with normal GFR<\/td>\n<td width=\"33%\">&gt;\/=90<\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\">2<\/td>\n<td width=\"33%\">Kidney damage with mild decrease\u00a0in GFR<\/td>\n<td width=\"33%\">60\u201389<\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\">3A<\/td>\n<td width=\"33%\">Mild-to-moderate decrease\u00a0in GFR<\/td>\n<td width=\"33%\">45\u201359<\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\">3B<\/td>\n<td width=\"33%\">Moderate-to-severe decrease\u00a0in GFR<\/td>\n<td width=\"33%\">30\u201344<\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\">4<\/td>\n<td width=\"33%\">Severe decrease in GFR<\/td>\n<td width=\"33%\">15\u201329<\/td>\n<\/tr>\n<tr valign=\"TOP\">\n<td style=\"text-align: center;\" width=\"33%\">5<\/td>\n<td width=\"33%\">End-stage renal disease<\/td>\n<td width=\"33%\">&lt;15<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>The stage of acute kidney injury is determined according to the Kidney Disease\u00a0Improving Global Outcomes Acute Kidney Injury Classification, and that\u00a0of chronic kidney disease according to the glomerular filtration rate (GFR).\u00a0Kidney damage is usually detected by means of an increased urinary \u00a0albumin-to-creatinine ratio. To convert the values for creatinine to micromoles per liter,\u00a0multiply by 88.4.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>References:<\/strong><\/p>\n<ol>\n<li>Chawla LS, Eggers PW, Star RA, Kimmel PL. Acute kidney injury and chronic kidney disease as interconnected syndromes. N Engl J Med. 2014 Jul 3;371(1):58-66.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24988558\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Stevens PE, Levin A; Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group Members. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline.\u00a0Ann Intern Med. 2013 Jun 4;158(11):825-30.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23732715\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Levey AS, Coresh J. Chronic kidney disease. Lancet. 2012 Jan 14;379(9811):165-80.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21840587\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Levey AS, Grams ME, Inker LA. Uses of GFR and Albuminuria Level in Acute and Chronic Kidney Disease. N Engl J Med. 2022 Jun 2;386(22):2120-2128. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35648704\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Created Sep 12, 2014.<br \/>\nUp-date Apr 08, 2026.<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[473],"tags":[231,230,146,904,166,903,902,51,901,348,149,900,199],"class_list":["post-2362","post","type-post","status-publish","format-standard","hentry","category-nephrology","tag-acute","tag-aguda","tag-chronic","tag-ckd","tag-clasificacion","tag-classifications","tag-cronico","tag-disease","tag-fallo","tag-injuria","tag-injury","tag-kidney","tag-renal"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/2362","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/comments?post=2362"}],"version-history":[{"count":4,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/2362\/revisions"}],"predecessor-version":[{"id":10737,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/2362\/revisions\/10737"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/media?parent=2362"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/categories?post=2362"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/tags?post=2362"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}