{"id":2370,"date":"2014-03-06T12:50:33","date_gmt":"2014-03-06T12:50:33","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/sdic\/"},"modified":"2026-10-29T19:58:01","modified_gmt":"2026-10-29T19:58:01","slug":"sdic","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/sdic\/","title":{"rendered":"Diagnostic Scoring System for Disseminated Intravascular Coagulation (DIC)"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>Disseminated intravascular coagulation is a clinicopathological diagnosis of a disorder that is defined by the International Society on Thrombosis\u00a0<span style=\"line-height: 1.3em;\">and Hemostasis (ISTH) as &#8220;an acquired syndrome <\/span><span style=\"line-height: 1.3em;\">characterized by the intravascular activation of coagulation with loss of localization arising from different causes&#8221;. This condition typically originates in the microvasculature and can cause damage of such severity that it leads to organ dysfunction. It can be identified on the basis of a scoring system developed by the ISTH. <\/span><br \/>\n<!--more--><br \/>\n<strong>Diagnostic Scoring System for Disseminated Intravascular Coagulation (DIC)<\/strong><br \/>\nRisk assessment: Does the patient have an underlying disorder known to be associated with overt DIC?<\/p>\n<ul>\n<li><span style=\"line-height: 1.3em;\">If yes, proceed with this algorithm<\/span><\/li>\n<li><span style=\"line-height: 1.3em;\">If no, do not use this algorithm<\/span><\/li>\n<\/ul>\n<p>Order global coagulation tests (prothrombin time, platelet count, fibrinogen, fibrin-related marker)<br \/>\nScore the test results as follows:<\/p>\n<ul>\n<li><span style=\"line-height: 1.3em;\">Platelet count: 50,000 to 100,000 per mm3<\/span><span style=\"line-height: 1.3em;\">, 1 point; &lt;50,000 per mm3<\/span><span style=\"line-height: 1.3em;\">, 2 points<\/span><\/li>\n<li><span style=\"line-height: 1.3em;\">Elevated fibrin-related marker (e.g., d-dimer, fibrin degradation products): no increase, 0 points; moderate increase, 2 points; strong <\/span><span style=\"line-height: 1.3em;\">increase, 3 points<\/span><\/li>\n<li><span style=\"line-height: 1.3em;\">Prolonged prothrombin time: &lt;3 sec, 0 points; &gt;\/=3 sec but &lt;6 sec, 1 point; &gt;\/=6 sec, 2 points<\/span><\/li>\n<li><span style=\"line-height: 1.3em;\">Fibrinogen level: &gt;\/=1 g per liter, 0 points; &lt;1 g per liter, 1 point<\/span><\/li>\n<\/ul>\n<p>Calculate the score as follows:<\/p>\n<ul>\n<li><span style=\"line-height: 1.3em;\">&gt;\/=5 points: compatible with overt DIC; repeat scoring daily<\/span><\/li>\n<li><span style=\"line-height: 1.3em;\">&lt;5 points: suggestive of non overt DIC; repeat scoring within next 1 to 2 days<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><span style=\"line-height: 1.3em;\"><strong>References:<\/strong><\/span><\/p>\n<ol>\n<li>Hunt BJ. Bleeding and coagulopathies in critical care. N Engl J Med. 2014 Feb 27;370(9):847-59.<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24571757\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Toh CH, Hoots WK; SSC on Disseminated Intravascular Coagulation of the ISTH. The scoring system of the Scientific and Standardisation Committee on Disseminated Intravascular Coagulation of the International Society on Thrombosis and Haemostasis: a 5-year overview. J Thromb Haemost. 2007 Mar;5(3):604-6.<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17096704\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Iba T, Levy JH, Maier CL, Helms J, Umemura Y, Moore H, Othman M, Thachil J, Connors JM, Levi M, Scarlatescu E. Updated definition and scoring of disseminated intravascular coagulation in 2025: communication from the ISTH SSC Subcommittee on Disseminated Intravascular Coagulation. J Thromb Haemost. 2025 Jul;23(7):2356-2362. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40216223\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Created May 29, 2014.<br \/>\nUp date Oct 29, 2026.<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"footnotes":""},"categories":[171],"tags":[942,941,14,13,947,946,945,944,450,794,494,507],"class_list":["post-2370","post","type-post","status-publish","format-standard","hentry","category-hematology","tag-coagulacion","tag-coagulation","tag-diagnostic","tag-diagnostico","tag-dic","tag-diseminada","tag-disseminated","tag-intravascular","tag-score","tag-scoring","tag-sistema","tag-system"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - 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