{"id":2535,"date":"2009-03-03T18:53:23","date_gmt":"2009-03-03T18:53:23","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/neuropnd\/"},"modified":"2025-05-14T19:10:58","modified_gmt":"2025-05-14T19:10:58","slug":"neuropnd","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/neuropnd\/","title":{"rendered":"Diagnostic Criteria of Paraneoplastic Neurological Disorder (PND) of the CNS"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p><\/p>\n<div class=\"Section1\">\n<p class=\"MsoNormal\"><strong>Definite PND<\/strong><\/p>\n<ol>\n<li>Classic syndrome <em>with<\/em> cancer diagnosed within 5 years of neurological symptom development<\/li>\n<li><span class=\"SpellE\">Nonclassic<\/span> syndrome that resolves or significantly improves after cancer treatment<\/li>\n<li><span class=\"SpellE\">Nonclassic<\/span> syndrome <em>with<\/em> cancer diagnosed within 5 years of neurological symptom development <em>and<\/em> positive <span class=\"SpellE\">antineuronal<\/span> antibodies<\/li>\n<li>Neurological syndrome (classic or not) <em>without<\/em> cancer and <em>with<\/em> well-characterized <span class=\"SpellE\">antineuronal<\/span> antibodies<\/li>\n<\/ol>\n<p><!--more--><\/p>\n<p class=\"MsoNormal\"><strong>Possible PND<\/strong><\/p>\n<ol style=\"margin-top: 0cm;\">\n<li class=\"MsoNormal\">Classic syndrome <em>with<\/em> high risk of cancer, <em>without<\/em> <span class=\"SpellE\">antineuronal<\/span> antibodies<\/li>\n<li class=\"MsoNormal\">Neurological syndrome (classic or not) <em>without<\/em> cancer and <em>with<\/em> partially characterized <span class=\"SpellE\">antineuronal<\/span> antibodies<\/li>\n<li class=\"MsoNormal\"><span class=\"SpellE\">Nonclassic<\/span> syndrome <em>with<\/em> cancer diagnosed within 2 years of neurological symptom development, <em>without<\/em> <span class=\"SpellE\">antineuronal<\/span> antibodies<\/li>\n<\/ol>\n<p class=\"MsoNormal\">PND, <span class=\"SpellE\">paraneoplastic<\/span> neurological disorder; CNS, central nervous system<\/p>\n<\/div>\n<div class=\"Section1\"><\/div>\n<div class=\"Section1\">\n<div class=\"Section1\">\n<div class=\"Section1\">\n<div class=\"Section1\">\n<p class=\"MsoNormal\"><strong>References:<\/strong><\/p>\n<div class=\"Section1\">\n<div class=\"Section1\">\n<div class=\"Section1\">\n<div class=\"Section1\">\n<div class=\"Section1\">\n<div class=\"Section1\">\n<ol>\n<li>\n<p class=\"MsoNormal\"><span class=\"SpellE\"><span class=\"GramE\">Bataller<\/span><\/span><span class=\"GramE\"> L, <span class=\"SpellE\">Dalmau<\/span> JO.<\/span> <span class=\"SpellE\">Paraneoplastic<\/span> disorders of the central nervous system: update on diagnostic criteria and treatment. <span class=\"SpellE\">Semin<\/span> <span class=\"SpellE\">Neurol<\/span>. 2004 Dec<span class=\"GramE\">;24<\/span>(4):461-71. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15637657\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/p>\n<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<p>Created: May 15, 2005<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[2],"tags":[916,16,15,14,13,85,1322,1639,1300,1638,1637,1636,5,905],"class_list":["post-2535","post","type-post","status-publish","format-standard","hentry","category-neurology","tag-cns","tag-criteria","tag-criterios","tag-diagnostic","tag-diagnostico","tag-disorder","tag-endocrinology","tag-neurological","tag-neurology","tag-paraneoplasico","tag-paraneoplastic","tag-pnd","tag-sindrome","tag-snc"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/2535","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/comments?post=2535"}],"version-history":[{"count":3,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/2535\/revisions"}],"predecessor-version":[{"id":9135,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/2535\/revisions\/9135"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/media?parent=2535"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/categories?post=2535"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/tags?post=2535"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}