{"id":2568,"date":"2009-02-28T20:03:18","date_gmt":"2009-02-28T20:03:18","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/gaschild\/"},"modified":"2025-05-14T19:11:54","modified_gmt":"2025-05-14T19:11:54","slug":"gaschild","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/gaschild\/","title":{"rendered":"Child-Pugh Classification of Severity of Liver Disease"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p><\/p>\n<div class=\"Section1\">\n<p class=\"MsoNormal\">Modified Child-Pugh classification of severity of liver disease according to the degree of ascites, the plasma concentrations of bilirrubin and albumin, the prothrombin time, and the degree of encephalopathy.<\/p>\n<p><!--more--><\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 51px;\" rowspan=\"2\"><strong>Parameter<\/strong><\/td>\n<td style=\"width: 25%; height: 27px; text-align: center;\" colspan=\"3\"><strong style=\"text-align: center;\">Points assigned<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px; text-align: center;\">1<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\">2<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\">3<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Ascites<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">Absent<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">Slight<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">Moderate<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Bilirrubin, mg\/dL<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">&lt;\/= 2<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">2-3<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">&gt;3<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Albumin, g\/dL<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">&gt;3.5<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">2.8-3.5<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">&lt;2.8<\/span><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">\n<p class=\"MsoNormal\" style=\"margin-top: 0pt; margin-bottom: 0pt;\">Prothrombin time<\/p>\n<p class=\"MsoNormal\" style=\"margin-top: 0pt; margin-bottom: 0pt;\">* Seconds over control<\/p>\n<p class=\"MsoNormal\" style=\"margin-top: 0pt; margin-bottom: 0pt;\">* INR<\/p>\n<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\">\n<p class=\"MsoNormal\" style=\"margin-top: 0pt; margin-bottom: 0pt;\">1-3<\/p>\n<p class=\"MsoNormal\" style=\"margin-top: 0pt; margin-bottom: 0pt;\">&lt;1.8<\/p>\n<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\">\n<p class=\"MsoNormal\" style=\"margin-top: 0pt; margin-bottom: 0pt; text-align: center;\">4-6<\/p>\n<p class=\"MsoNormal\" style=\"margin-top: 0pt; margin-bottom: 0pt; text-align: center;\">1.8-2.3<\/p>\n<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\">\n<p class=\"MsoNormal\" style=\"margin-top: 0pt; margin-bottom: 0pt;\">&gt;6<\/p>\n<p class=\"MsoNormal\" style=\"margin-top: 0pt; margin-bottom: 0pt;\">&gt;2.3<\/p>\n<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 25%; height: 24px;\">Encephalopathy<\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">None<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">Grade 1-2<\/span><\/td>\n<td style=\"width: 25%; height: 24px; text-align: center;\"><span style=\"text-align: -webkit-center;\">Grade 3-4<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div class=\"Section1\">\n<p class=\"MsoNormal\">A total score of 5-6 is considered grade A (well-compensated disease); 7-9 is grade B (significant functional compromise); and 10-15 is grade C (descompensated disease). These grades correlate with one- and two-year patient survival.<\/p>\n<\/div>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr>\n<td style=\"width: 25%;\"><strong>Grade<\/strong><\/td>\n<td style=\"width: 25%; text-align: center;\"><strong style=\"text-align: center;\">Points<\/strong><\/td>\n<td style=\"width: 25%; text-align: center;\"><strong style=\"text-align: center;\">One-year patient survival (%)<\/strong><\/td>\n<td style=\"width: 25%; text-align: center;\"><strong style=\"text-align: center;\">Two-year patient survival (%)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%;\">A: well-compensated disease<\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"text-align: center;\">5-6<\/span><\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"text-align: center;\">100<\/span><\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"text-align: center;\">85<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%;\">B: significant functional compromise<\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"text-align: center;\">7-9<\/span><\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"text-align: center;\">80<\/span><\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"text-align: center;\">60<\/span><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 25%;\">C: descompensated disease<\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"text-align: center;\">10-15<\/span><\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"text-align: center;\">45<\/span><\/td>\n<td style=\"width: 25%; text-align: center;\"><span style=\"text-align: center;\">35<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<div class=\"Section1\">\n<p class=\"MsoNormal\"><strong>References:<\/strong><\/p>\n<\/div>\n<ol>\n<li class=\"MsoNormal\">Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973 Aug;60(8):646-9. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/4541913\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li class=\"MsoNormal\">Lucey MR, Brown KA, Everson GT, Fung JJ, Gish R, Keeffe EB, Kneteman NM, Lake JR, Martin P, McDiarmid SV, Rakela J, Shiffman ML, So SK, Wiesner RH. Minimal criteria for placement of adults on the liver transplant waiting list: a report of a national conference organized by the American Society of Transplant Physicians and the American Association for the Study of Liver Diseases. Liver Transpl Surg. 1997 Nov;3(6):628-37. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9404965\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Created: February 16, 2006<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[53],"tags":[1737,166,167,51,1413,529,1725,524,1736,226,180],"class_list":["post-2568","post","type-post","status-publish","format-standard","hentry","category-gastroenterology","tag-child","tag-clasificacion","tag-classification","tag-disease","tag-gastroenterology","tag-hepatico","tag-higado","tag-liver","tag-pugh","tag-severidad","tag-severity"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - 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