{"id":5603,"date":"2013-09-10T14:52:33","date_gmt":"2013-09-10T14:52:33","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/alcoholic-liver-disease\/"},"modified":"2025-05-13T20:27:52","modified_gmt":"2025-05-13T20:27:52","slug":"alcoholic-liver-disease","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/alcoholic-liver-disease\/","title":{"rendered":"Typical Laboratory Abnormalities in Alcoholic Liver Disease (ALD)"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>Alcoholic liver disease (ALD) encompasses a spectrum of injury, ranging from simple steatosis to frank cirrhosis.<br \/>\n<!--more--><br \/>\n<strong>Typical Laboratory Abnormalities in ALD<\/strong><br \/>\nSerum enzymes<\/p>\n<ul>\n<li>AST &gt;&gt;&gt; ALT: Both usually &lt;300 IU\/L<\/li>\n<li>Alkaline phosphatase (ALP) and g-glutamyl transpeptidase (GGT): Both usually elevated to a variable degree<\/li>\n<\/ul>\n<p>Metabolic alterations<\/p>\n<ul>\n<li>Hyperglycemia<\/li>\n<li>Hypertrygleridemia<\/li>\n<li>Hyperuricemia<\/li>\n<li>Electrolyte abnormalities: low potassium, magnesium and phosphorus<\/li>\n<\/ul>\n<p>Tests of liver function<\/p>\n<ul>\n<li>Serum albumin, prothrombin time, and serum bilirubin usually normal until significant liver injury present<\/li>\n<\/ul>\n<p>Hematological abnormalities<\/p>\n<ul>\n<li>Mild anemia common (usually macrocytic)<\/li>\n<li>Platelets (normal to markedly decreased)<\/li>\n<li>Elevated white blood cell count: Leukemoid reactions associated with alcoholic hepatitis<\/li>\n<\/ul>\n<p>Abbreviations: AST, aspartate aminotransferase; \u00a0ALT, alanine aminotransferase<\/p>\n<p>&nbsp;<\/p>\n<p><strong>References:<\/strong><\/p>\n<ol>\n<li>O&#8217;Shea RS, Dasarathy S, McCullough AJ. Alcoholic liver disease. Am J Gastroenterol. 2010 Jan;105(1):14-32. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19904248\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>McCullough AJ, O&#8217;Connor JF. Alcoholic liver disease: proposed recommendations for the American College of Gastroenterology. Am J Gastroenterol. 1998 Nov;93(11):2022-36. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9820369\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Created Sep 10, 2013.<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[53],"tags":[1915,1735,2008,2007,1914,51,50,529,1725,938,937,524,1141,1140],"class_list":["post-5603","post","type-post","status-publish","format-standard","hentry","category-gastroenterology","tag-abnormalities","tag-alcoholic","tag-alcoholico","tag-ald","tag-anormalidades","tag-disease","tag-enfermedad","tag-hepatico","tag-higado","tag-laboratorio","tag-laboratory","tag-liver","tag-tipico","tag-typical"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/5603","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/comments?post=5603"}],"version-history":[{"count":3,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/5603\/revisions"}],"predecessor-version":[{"id":9297,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/5603\/revisions\/9297"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/media?parent=5603"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/categories?post=5603"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/tags?post=5603"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}