{"id":5700,"date":"2004-07-07T12:00:00","date_gmt":"2004-07-07T12:00:00","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/neurocys\/"},"modified":"2025-09-02T19:55:59","modified_gmt":"2025-09-02T19:55:59","slug":"neurocys","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/neurocys\/","title":{"rendered":"Diagnostic Criteria for Neurocysticercosis"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>Neurocysticercosis is the most common helminthic infection of the CNS but its diagnosis remains difficult. Clinical manifestations are nonspecific, most neuroimaging findings are not pathognomonic, and some serologic tests have low sensitivity and specificity. <!--more--><\/p>\n<p><strong>Diagnostic Criteria for Neurocysticercosis<\/strong><\/p>\n<p class=\"MsoNormal\"><strong>Absolute <\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Histologic demonstration of the parasite from biopsy of a brain or spinal cord lesion<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Cystic lesions showing the scolex on CT or MRI<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Direct visualization of subretinal parasites by fundoscopic examination<\/p>\n<p class=\"MsoNormal\"><strong>Major <\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Lesions highly suggestive of neurocysticercosis on neuroimaging studies<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Positive serum immunoblot for the detection of anticysticercal antibodies<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Resolution of intracranial cystic lesions after therapy with albendazole or praziquantel<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Spontaneous resolution of small single enhancing lesions<\/p>\n<p class=\"MsoNormal\"><strong>Minor <\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Lesions compatible with neurocysticercosis on neuroimaging studies<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Clinical manifestations suggestive of neurocysticercosis<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Positive CSF ELISA for detection of anticysticercal antibodies or cysticercal antigens<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Cysticercosis outside the central nervous system<\/p>\n<p class=\"MsoNormal\"><strong>Epidemiologic <\/strong><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Evidence of a household contact with <em>T. solium <\/em>infection<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>Individuals coming from or living in an area where cysticercosis is endemic<\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 27pt; text-indent: -18pt; margin-top: 0pt; margin-bottom: 0pt;\"><span style=\"font-family: Symbol;\">\u00b7 <\/span>History of frequent travel to disease-endemic areas<\/p>\n<p class=\"MsoNormal\">CSF, cerebrospinal fluid; ELISA, enzyme-linked immunosorbent assay.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p class=\"MsoNormal\"><strong>References:<\/strong><\/p>\n<ol style=\"margin-top: 0cm;\">\n<li class=\"MsoNormal\">Del Brutto OH, Rajshekhar V, White Jr AC, Tsang VCW, Nash TE, Takayanagui OM, et al. Proposed diagnostic criteria for neurocysticercosis. Neurology 2001; 57: 177-83. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11480424\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li class=\"MsoNormal\">Garcia HH, Evans CA, Nash TE, Takayanagui OM, White AC Jr, Botero D, Rajshekhar V, Tsang VC, Schantz PM, Allan JC, Flisser A, Correa D, Sarti E, Friedland JS, Martinez SM, Gonzalez AE, Gilman RH, Del Brutto OH.Current consensus guidelines for treatment of neurocysticercosis. Clin Microbiol Rev. 2002 Oct;15(4):747-56. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12364377\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Singh G, Chomba M, Sander JW. Neurocysticercosis: current diagnostic and treatment paradigms. Curr Opin Neurol. 2025 Aug 1;38(4):380-387. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40605684\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Created: Sep 08, 2005<br \/>\nUpdate: Sep 02, 2025<\/p>\n<p class=\"MsoNormal\">\n<p><\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[2],"tags":[16,15,14,13,492,493,1300,766],"class_list":["post-5700","post","type-post","status-publish","format-standard","hentry","category-neurology","tag-criteria","tag-criterios","tag-diagnostic","tag-diagnostico","tag-neurocisticercosis","tag-neurocysticercosis","tag-neurology","tag-surgery"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/5700","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/comments?post=5700"}],"version-history":[{"count":4,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/5700\/revisions"}],"predecessor-version":[{"id":10548,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/5700\/revisions\/10548"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/media?parent=5700"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/categories?post=5700"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/tags?post=5700"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}