{"id":7883,"date":"2020-08-19T20:38:39","date_gmt":"2020-08-19T20:38:39","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/?p=7883"},"modified":"2026-01-07T20:06:23","modified_gmt":"2026-01-07T20:06:23","slug":"polycystic-kidney","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/polycystic-kidney\/","title":{"rendered":"New Diagnostic Criteria Proposed for Polycystic Kidney Disease"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney disease. Enlarging cysts within the kidneys are the clinical hallmark of the disease. Renal manifestations include varying degrees of kidney injury, urinary tract infections, kidney stones, and hematuria. Extrarenal manifestations can include pain, hypertension, left ventricular hypertrophy, hepatic cysts, intracranial aneurysm, diverticulosis, and abdominal and inguinal hernias.<!--more--><\/p>\n<p><strong>Radiographic Diagnostic Criteria for ADPKD<\/strong><\/p>\n<table style=\"border-collapse: collapse; width: 100%;\" border=\"1\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 24px;\"><\/td>\n<td style=\"width: 33.3333%; height: 24px;\"><strong>Age (Years)<\/strong><\/td>\n<td style=\"width: 33.3333%; height: 24px;\"><strong>Number of Cysts<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 72px;\" rowspan=\"3\">Ultrasonography (at-risk of ADPKD type 1)<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">&lt; 30<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 2 in one or both kidneys<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 24px;\">30 to 59<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 2 in each kidney<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 60<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 4 in each kidney<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 72px;\" rowspan=\"3\">Ultrasonography (at risk and unknown genotype)<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">15 to 39<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 3 in one or both kidneys<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 24px;\">40 to 59<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 2 in each kidney<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 60<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 4 in each kidney<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 24px;\" rowspan=\"4\">Magnetic resonance imaging (at risk)<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">&lt; 30<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 5 in each kidney<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 24px;\">30 to 44<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">\u2265 6 in each kidney<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 24px;\">45 to 59 (females)<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">&gt; 6 in each kidney<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.3333%; height: 24px;\">45 to 59 (males)<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">&gt; 9 in each kidney<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p><strong>References:<\/strong><\/p>\n<ol>\n<li>Gradzik M, Niemczyk M, Go\u0142\u0119biowski M, P\u0105czek L. Diagnostic Imaging of Autosomal Dominant Polycystic Kidney Disease. Pol J Radiol. 2016;81:441-453. Published 2016 Sep 17. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27733888\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Srivastava A, Patel N. Autosomal dominant polycystic kidney disease. Am Fam Physician. 2014;90(5):303-307. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25251090\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Pei Y, Obaji J, Dupuis A, et al. Unified criteria for ultrasonographic diagnosis of ADPKD.\u00a0J Am Soc Nephrol. 2009;20(1):205-212. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18945943\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Gimpel C, Bergmann C, Bockenhauer D, et al. International consensus statement on the diagnosis and management of autosomal dominant polycystic kidney disease in children and young people. Nat Rev Nephrol. 2019;15(11):713-726. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31118499\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>Gordon CE, Garimella PS, Perrone RD, Miskulin DC. Autosomal Dominant Polycystic Kidney Disease: Core Curriculum 2025. Am J Kidney Dis. 2025 Oct;86(4):525-542. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40844441\/\" target=\"_blank\" rel=\"noopener\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Created Aug 18, 2020.<br \/>\nUp-date Jan 07, 2026.<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[473],"tags":[16,15,14,13,51,50,900,2238,1653,199],"class_list":["post-7883","post","type-post","status-publish","format-standard","hentry","category-nephrology","tag-criteria","tag-criterios","tag-diagnostic","tag-diagnostico","tag-disease","tag-enfermedad","tag-kidney","tag-poliquistica","tag-polycystic","tag-renal"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/7883","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/comments?post=7883"}],"version-history":[{"count":10,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/7883\/revisions"}],"predecessor-version":[{"id":10572,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/7883\/revisions\/10572"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/media?parent=7883"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/categories?post=7883"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/tags?post=7883"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}