{"id":8661,"date":"2021-06-25T14:23:53","date_gmt":"2021-06-25T14:23:53","guid":{"rendered":"https:\/\/medicalcriteria.com\/web\/?p=8661"},"modified":"2026-01-05T18:51:03","modified_gmt":"2026-01-05T18:51:03","slug":"endometrial-cancer","status":"publish","type":"post","link":"https:\/\/medicalcriteria.com\/web\/endometrial-cancer\/","title":{"rendered":"Staging Systems for Endometrial Cancer"},"content":{"rendered":"<div class=\"99c380e4b4a7b96c35d7ddf7dcb434e8\" data-index=\"1\" style=\"float: none; margin:0px 0 0px 0; text-align:center;\">\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- MC 2019- Horizontal -->\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-client=\"ca-pub-0127150553352455\"\r\n     data-ad-slot=\"3806776041\"\r\n     data-ad-format=\"auto\"\r\n     data-full-width-responsive=\"true\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\n<\/div>\n<p>Staging is performed with the use of the International Federation of Gynecology and Obstetrics (FIGO) system and the tumor\u2013node\u2013metastasis (TNM) system.<!--more--><\/p>\n<p><strong>Staging Systems for Endometrial Cancer<\/strong><\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 816px;\" border=\"1\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 99.9999%; text-align: center; height: 24px;\" colspan=\"3\"><strong>Primary Tumor (T)<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 48px;\">TNM system,<br \/>\nT category<\/td>\n<td style=\"width: 9.1575%; text-align: center; height: 48px;\">FIGO<br \/>\nsystem<\/td>\n<td style=\"width: 78.0219%; height: 48px;\">T criteria<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 24px;\">TX<\/td>\n<td style=\"width: 9.1575%; height: 24px;\"><\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Primary tumor cannot be assessed<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 24px;\">T0<\/td>\n<td style=\"width: 9.1575%; height: 24px;\"><\/td>\n<td style=\"width: 78.0219%; height: 24px;\">No evidence of primary tumor<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 24px;\">T1<\/td>\n<td style=\"width: 9.1575%; text-align: center; height: 24px;\">I<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Tumor confined to corpus uteri, including endocervical glandular involvement<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 24px;\">T1a<\/td>\n<td style=\"width: 9.1575%; text-align: center; height: 24px;\">IA<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Tumor limited to the endometrium or invading less than half of the myometrium<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 24px;\">T1b<\/td>\n<td style=\"width: 9.1575%; text-align: center; height: 24px;\">IB<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Tumor invading one half or more of the myometrium<\/td>\n<\/tr>\n<tr style=\"height: 72px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 72px;\">T2<\/td>\n<td style=\"width: 9.1575%; text-align: center; height: 72px;\">II<\/td>\n<td style=\"width: 78.0219%; height: 72px;\">Tumor invading the stromal connective tissue of the cervix but not extending beyond the uterus<br \/>\nDoes not include endocervical glandular involvement<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 24px;\">T3<\/td>\n<td style=\"width: 9.1575%; text-align: center; height: 24px;\">III<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Tumor involving serosa, adnexa, vagina, or parametrium<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 24px;\">T3a<\/td>\n<td style=\"width: 9.1575%; text-align: center; height: 24px;\">IIIA<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Tumor involving the serosa, adnexa, or both (direct extension or metastasis)<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 24px;\">T3b<\/td>\n<td style=\"width: 9.1575%; text-align: center; height: 24px;\">IIIB<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Vaginal involvement (direct extension or metastasis) or parametrial involvement<\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 48px;\">T4<\/td>\n<td style=\"width: 9.1575%; text-align: center; height: 48px;\">IV<\/td>\n<td style=\"width: 78.0219%; height: 48px;\">Tumor invading the bladder mucosa, bowel mucosa, or both<br \/>\nBullous edema is not sufficient to classify a tumor as T4<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; text-align: center; height: 24px;\" colspan=\"3\"><strong>Regional Lymph Nodes (N)<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"width: 12.8205%; height: 48px; text-align: center;\">TNM system,<br \/>\nN category<\/td>\n<td style=\"width: 9.1575%; height: 48px; text-align: center;\">FIGO<br \/>\nsystem<\/td>\n<td style=\"width: 78.0219%; height: 48px;\">N criteria<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; height: 24px; text-align: center;\">NX<\/td>\n<td style=\"width: 9.1575%; height: 24px;\"><\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Regional lymph nodes cannot be assessed<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; height: 24px; text-align: center;\">N0<\/td>\n<td style=\"width: 9.1575%; height: 24px;\"><\/td>\n<td style=\"width: 78.0219%; height: 24px;\">No regional lymph node metastasis<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; height: 24px; text-align: center;\">N0(i+)<\/td>\n<td style=\"width: 9.1575%; height: 24px;\"><\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Isolated tumor cells in regional lymph node, \u22640.2 mm\u00a0in diameter<\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"width: 12.8205%; height: 48px; text-align: center;\">N1mi<\/td>\n<td style=\"width: 9.1575%; height: 48px; text-align: center;\">IIIC1<\/td>\n<td style=\"width: 78.0219%; height: 48px;\">Regional lymph node micrometastasis (&gt;0.2 mm to\u00a02.0 mm in diameter) to pelvic lymph nodes<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; height: 24px; text-align: center;\">N1<\/td>\n<td style=\"width: 9.1575%; height: 24px; text-align: center;\">IIIC1<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Regional lymph node macrometastasis (&gt;2.0 mm in\u00a0diameter) to pelvic lymph nodes<\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"width: 12.8205%; height: 48px; text-align: center;\">N2mi<\/td>\n<td style=\"width: 9.1575%; height: 48px; text-align: center;\">IIIC2<\/td>\n<td style=\"width: 78.0219%; height: 48px;\">Regional lymph node micrometastasis (&gt;0.2 mm to\u00a02.0 mm in diameter) to paraaortic lymph nodes, with\u00a0or without positive pelvic lymph nodes<\/td>\n<\/tr>\n<tr style=\"height: 48px;\">\n<td style=\"width: 12.8205%; height: 48px; text-align: center;\">N2<\/td>\n<td style=\"width: 9.1575%; height: 48px; text-align: center;\">IIIC2<\/td>\n<td style=\"width: 78.0219%; height: 48px;\">Regional lymph node macrometastasis (&gt;2.0 mm in\u00a0diameter) to paraaortic lymph nodes, with or without\u00a0positive pelvic lymph nodes<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; height: 24px; text-align: center;\" colspan=\"3\"><strong>Distant Metastasis (M)<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; height: 24px; text-align: center;\">TNM system,<br \/>\nM category<\/td>\n<td style=\"width: 9.1575%; height: 24px; text-align: center;\">FIGO<br \/>\nsystem<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">M criteria<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; height: 24px; text-align: center;\">cM0<\/td>\n<td style=\"width: 9.1575%; height: 24px;\"><\/td>\n<td style=\"width: 78.0219%; height: 24px;\">No distant metastasis on clinical (c) assessment<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; height: 24px; text-align: center;\">cM1<\/td>\n<td style=\"width: 9.1575%; height: 24px; text-align: center;\">IVB<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Distant metastasis (includes metastasis to inguinal\u00a0lymph nodes, lung, liver, or bone or intraperitoneal disease)<br \/>\nAlso includes metastasis to pelvic or paraaortic lymph\u00a0nodes, vagina, uterine serosa, or adnexa<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.8205%; height: 24px; text-align: center;\">pM1<\/td>\n<td style=\"width: 9.1575%; height: 24px; text-align: center;\">IVB<\/td>\n<td style=\"width: 78.0219%; height: 24px;\">Distant metastasis (includes metastasis to inguinal\u00a0lymph nodes, liver, or bone or intraperitoneal disease) microscopically confirmed on pathological (p)\u00a0assessment<br \/>\nExcludes metastasis to pelvic or paraaortic lymph nodes,\u00a0vagina, uterine serosa, or adnexa<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>References:<\/strong><\/p>\n<ol>\n<li>Lu KH, Broaddus RR. Endometrial Cancer. N Engl J Med. 2020 Nov 19;383(21):2053-2064. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33207095\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<li>McCluggage WG. Pathologic Staging of Endometrial Carcinomas: Selected Areas of Difficulty. Adv Anat Pathol. 2018 Mar;25(2):71-84. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29356713\/\" target=\"_blank\" rel=\"noopener noreferrer\">[Medline]<\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Created Jun 18, 2021.<\/p>\n\n<div style=\"font-size: 0px; height: 0px; line-height: 0px; margin: 0; padding: 0; clear: both;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Sorry, this entry is only available in Espa\u00f1ol.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[87],"tags":[322,2389,2391,840,494,835,798],"class_list":["post-8661","post","type-post","status-publish","format-standard","hentry","category-obstetrics-gynecology","tag-cancer","tag-endometrial","tag-endometrio","tag-estadificacion","tag-sistema","tag-staging","tag-systems"],"modified_by":"Guillermo Firman","_links":{"self":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/8661","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/comments?post=8661"}],"version-history":[{"count":10,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/8661\/revisions"}],"predecessor-version":[{"id":8697,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/posts\/8661\/revisions\/8697"}],"wp:attachment":[{"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/media?parent=8661"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/categories?post=8661"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/medicalcriteria.com\/web\/wp-json\/wp\/v2\/tags?post=8661"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}