HMG CoA-reductase inhibitors or statins are clearly the most effective class of drugs for lowering LDL cholesterol. Those drugs have been associated with a beneficial impact on cardiovascular morbidity and mortality.
Effectiveness
Criteria for Evaluating the Effectiveness of Screening for a Risk Factor
Characteristics of the disease
1. Disease has serious consequences
2. Screening population has a high incidence* of disease
3. Risk factor is a good predictor of disease