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EULAR/ACR New Classification Criteria for Systemic Lupus Erythematosus (SLE)

The new EULAR/ACR classification criteria use anti-nuclear antibodies (ANA) as an entry criterion. (Non-infectious) fever is the one new criterion. All criteria items now have individual weights (from 2 to 10) and are structured in domains, within which only the highest item is counted. There is one common attribution rule, counting criteria only if there is no more likely alternative explanation. Ten points are sufficient for classification. The new criteria have reached a sensitivity of 96.1% and a specificity of 93.4%. Continue reading “EULAR/ACR New Classification Criteria for Systemic Lupus Erythematosus (SLE)”

Classification Criteria for IgG4-Related Disease

Immunoglobulin G4-related disease is an immune mediated condition resulting in disease in various organs of the body such as the pancreas, kidneys, salivary glands, lung, liver, lymph nodes, biliary tract and orbits of the eyes. The disease is recognized by a characteristic pattern of pathological, serological or clinical features shared amongst the organs system that are involved. In some cases, IgG4-RD can mimic malignant, infectious or inflammatory disorders and therefore distinguishing the disease is crucial. Continue reading “Classification Criteria for IgG4-Related Disease”

Classification Criteria for Discoid Lupus Erythematosus (DLE)

No universally recognized classification criteria currently exist for discoid lupus erythematosus (DLE), which has led to problematic heterogeneity in observational and interventional clinical studies across the field. Continue reading “Classification Criteria for Discoid Lupus Erythematosus (DLE)”

2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides

Chapel Hill Consensus Conference (CHCC) is a nomenclature system (nosology). It is neither a classification system that specifies what findings must be observed in a specific patient to classify that patient for clinical research nor a diagnostic system that directs clinical management. Continue reading “2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides”

Revised Diagnostic Criteria of Vogt-Koyanagi-Harada Disease (VKHD)

Vogt-Koyanagi-Harada disease (VKHD) is a bilateral, chronic granulomatous panuveitis associated with central nervous system, auditory, and integumentary manifestations. Continue reading “Revised Diagnostic Criteria of Vogt-Koyanagi-Harada Disease (VKHD)”

Revised Sapporo Criteria for Antiphospholipid Syndrome (APS)

Antiphospholipid antibody syndrome (APS) is an autoimmune disorder characterized by vascular thrombosis, complications during pregnancy, and the presence of antiphospholipid antibodies (APL) in plasma. Continue reading “Revised Sapporo Criteria for Antiphospholipid Syndrome (APS)”

2017 ACR–EULAR Classification Criteria for Primary Sjögren’s Syndrome

A diagnosis of primary Sjögren’s syndrome is often made on the basis of a classic triad of symptoms: dryness of the mouth and eyes, fatigue, and pain. Systemic complications, which are present in 30 to 40% of patients, may provide the first clues to the disease.
Continue reading “2017 ACR–EULAR Classification Criteria for Primary Sjögren’s Syndrome”

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