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Psoriasis Area Severity Index (PASI) Score

The Psoriasis Area Severity Index (PASI) is a tool used to measure the severity of psoriasis, a chronic autoimmune skin condition characterized by red, scaly patches on the skin. PASI takes into account the extent of psoriatic involvement (area) as well as the severity of erythema (redness), induration (thickness), and desquamation (scaling) present within the involved regions. It provides a quantitative assessment of psoriasis severity and is commonly used in clinical trials and practice to monitor disease progression and treatment efficacy. Continue reading “Psoriasis Area Severity Index (PASI) Score”

Diagnostic Criteria and Severity Grading of Acute Cholecystitis (TG18)

The diagnostic criteria for acute cholecystitis have high sensitivity (91.2%) and specificity (96.9%) and good diagnostic yield; therefore, their use as the diagnostic criteria for acute cholecystitis is recommended.

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Severity Criteria for Clostridium difficile Infection

Patients with severe disease may develop a colonic ileus or toxic dilatation and present with abdominal pain and distension but with minimal or no diarrhea. Complications of severe C. difficile colitis include dehydration, electrolyte disturbances, hypoalbuminemia, toxic megacolon, bowel perforation, hypotension, renal failure, systemic inflammatory response syndrome, sepsis, and death.

Diagnosis and Determination of Severity of Acute Cholecystitis

Acute cholecystitis is a very common complication of cholelithiasis, and as such is frequently encountered in surgical practice. TG07 diagnostic criteria are recognized as those to be recommended in current care for acute cholecystitis.
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International Clinical Diabetic Retinopathy and Diabetic Macular Edema Disease Severity Scales

The levels in this new diabetic retinopathy disease severity scale consist of five scales with increasing risks of retinopathy.
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Child-Pugh Classification of Severity of Liver Disease

Modified Child-Pugh classification of severity of liver disease according to the degree of ascites, the plasma concentrations of bilirrubin and albumin, the prothrombin time, and the degree of encephalopathy.

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GOLD Staging System for Chronic Obstructive Lung Disease (COPD) Severity

The European Respiratory Society (ERS) diagnostic criteria for COPD include the following symptoms: coughing, sputum production and/or dyspnoea, as well as a history of exposure to risk factors for COPD. The diagnosis is confirmed by a post-bronchodilator FEV1/FVC < 0.7 in spirometry, as sign of the airflow limitation that is not fully reversible.

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GINA Classification of Asthma Severity

The Global Initiative for Asthma (GINA) works with health care professionals and public health officials around the world to reduce asthma prevalence, morbidity, and mortality. The gold standard in classifying severity of asthma is the GINA classification.

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