Unifying Concepts

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Management of Acne Vulgaris

Acne is a primary inflammatory disorder involving the pilosebaceous unit. The pathogenesis is multifactorial, involving four key factors with interrelated mechanisms: increased sebum production, hyperkeratinization of the follicular infundibulum, inflammation, and Cutibacterium acnes (formerly Propionibacterium acnes). Continue reading “Management of Acne Vulgaris”

Diagnostic Criteria in Sézary’s Syndrome (SS)

Sézary Syndrome corresponds to 3% of all cutaneous lymphomas, and it is characterized by a triad of manifestations: erythrodermia with pruritus, limphonodomegalia and atypical circulating lymphocytes (referred to as Sézary or Lutzner cells). Associated clinical manifestations include lagophthalmos, alopecia, palmoplantar hyperkeratosis and onycodystrophy. Erythrodermia may be the progression of previous patches and plaques, developing from idiopathic erythrodermia or emerging de novo.
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Diagnostic Criteria for Alopecia Areata

Alopecia areata is manifested as the loss of hair in well-circumscribed patches of normal-appearing skin, most commonly on the scalp and in the region of the beard. The onset is typically rapid, and the disease can progress to the point where all the hair is lost on the scalp (alopecia areata totalis) or even on the whole body (alopecia areata universalis).
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Diagnosis and Indications for Treatment of Molluscum Contagiosum

Molluscum contagiosum is generally a benign disease consisting of pearly, flesh-colored, umbilicated skin lesions 2 to 5 mm in diameter with a characteristic dimple at the center. Continue reading “Diagnosis and Indications for Treatment of Molluscum Contagiosum”

Diagnostic Criteria for Atopic Dermatitis (AD)

Hanifin and Rajka Diagnostic Criteria for Atopic Dermatitis (AD)

Major criteria: Must have three or more of:

1. Pruritus
2. Typical morphology and distribution

    • Flexural lichenification or linearity in adults
    • Facial and extensor involvement in infants and children

Continue reading “Diagnostic Criteria for Atopic Dermatitis (AD)”

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