New Diagnostic and Treatment Criteria for Hypertension in Adults

The definition of hypertension was recently changed by the American College of Cardiology – American Heart Association to a systolic arterial pressure of more than
130 mm Hg, a diastolic pressure of more than 80 mm Hg, or both. Continue reading

Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease characterized by chronic, profound, disabling, and unexplained fatigue. Continue reading

STOPP/START Criteria for Potentially Inappropriate Prescribing in Older People

Adverse drug reactions (ADRs) in older people currently represent a serious and growing public health problem. Polypharmacy and inappropriate prescribing (IP) are wellknown risk factors for ADRs, which commonly cause adverse clinical outcomes in older people IP encompasses potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs). STOPP/START criteria for potential IP in older people recognise the dual nature of IP by including a list of PIMs (STOPP criteria) and PPOs (START criteria). Continue reading

WHO Diagnostic Criteria for Prefibrotic or Early-Stage Myelofibrosis (pre-PMF)

Prefibrotic myelofibrosis (pre-PMF) is a distinct entity among chronic myeloproliferative neoplasm diagnosed according to the revised WHO classification. The clinical picture is heterogeneous, ranging from isolated thrombocytosis, mimicking essential thrombocythemia (ET), to symptoms of high-risk PMF. Continue reading

DSM-5 Diagnostic Criteria for Schizophrenia

Schizophrenia is a psychiatric syndrome characterized by psychotic symptoms of hallucinations, delusions, and disorganized speech, by negative symptoms such as decreased motivation and diminished expressiveness, and by cognitive deficits involving impaired executive functions, memory, and speed of mental processing. Continue reading

Revised Diagnostic Criteria for Restless Legs Syndrome (RLS)

Restless legs syndrome (RLS), a neurological sensorimotor disease often profoundly disturbing sleep and quality of life has variable expression influenced by genetic, environmental and medical factors. The symptoms vary considerably in frequency from less than once a month or year to daily and severity from mildly annoying to disabling. Symptoms may also remit for various periods of time. Continue reading

Revised Criteria for Mild Cognitive Impairment (MCI)

Mild cognitive impairment (MCI) is a common condition in the elderly. It is characterized by deterioration of memory, attention, and cognitive function that is beyond what is expected based on age and educational level. MCI does not interfere significantly with individuals’ daily activities. Continue reading

Diagnostic Criteria for the Brugada Syndrome (BrS)

Brugada syndrome (BrS) is a rare inherited arrhythmia syndrome leading to an increased risk of sudden cardiac death, despite a structurally normal heart. Diagnosis is based on a specific electrocardiogram pattern, observed either spontaneously or during a sodium channel blocker test. Continue reading