Opioid analgesics (termed opioids in this report) are a class of drugs commonly prescribed to treat moderate to severe pain. Opioids include drugs available by prescription such as oxycodone, hydrocodone, codeine, morphine, and fentanyl. Opioids also include illicit substances such as heroin and fentanyl. Although often prescribed to control pain, opioids may also produce feelings of euphoria and sedation which may lead to misuse of opioids resulting in opioid use disorder. Continue reading “DSM-5 Diagnostic Criteria for Opioid Use Disorder”
Anaemia is a frequent finding in cancer patients and should be carefully assessed. Additional causes of anaemia such as iron deficiency, bleeding, nutritional defects or haemolysis should be corrected prior to erythropoietic protein therapy. The following recommendations are related to adult cancer patients with solid tumours or haematological malignancies:
Continue reading “Guidelines for the Use of Erythropoietic Proteins in Anaemic Patients with Cancer”
The red blood cell transfusions should not be dictated by a single hemoglobin “trigger” but instead should be based on the patient’s risks of developing complications of inadequate oxygenation. Red blood cell transfusion is rarely indicated when the hemoglobin concentration is greater than 10 g/dL and is almost always indicated when it is less than 6 g/dL.
Continue reading “Guidelines for the Clinical Use of Red Cell Transfusions”
In addition to the prediction of cardiovascular risk, ambulatory blood-pressure monitoring, when used in conjunction with clinic blood-pressure assessments, is of potential value in a variety of other clinical conditions. Some of these conditions are:
Continue reading “Recommendations for the Use of Ambulatory Blood-Pressure Monitoring”