Spontaneous rupture of membranes (ROM) is a normal component of labor and delivery. Premature ROM (PROM) refers to rupture of the fetal membranes prior to the onset of labor irrespective of gestational age. Once the membranes rupture, delivery is recommended when the risk of ascending infection outweighs the risk of prematurity. When PROM occurs at term, labor typically ensues spontaneously or is induced within 12 to 24 hours. The preterm PROM is defined as PROM occurring prior to 37 weeks of gestation. Continue reading “Risk Factors for Spontaneous Preterm Premature Rupture of Membranes”