These updated definitions and clinical criteria should replace previous definitions, offer greater consistency for epidemiologic studies and clinical trials, and facilitate earlier recognition and more timely management of patients with sepsis or at risk of developing sepsis. Continue reading
There are several tools available to evaluate health websites. Most of them list criteria that reliable websites should meet. Here is a summary of the main criteria. Continue reading
Opioid analgesics (termed opioids in this report) are a class of drugs commonly prescribed to treat moderate to severe pain. Opioids include drugs available by prescription such as oxycodone, hydrocodone, codeine, morphine, and fentanyl. Opioids also include illicit substances such as heroin and fentanyl. Although often prescribed to control pain, opioids may also produce feelings of euphoria and sedation which may lead to misuse of opioids resulting in opioid use disorder. Continue reading
The diagnosis of transient ischemic attack (TIA) can be notoriously difficult, mainly because it is often solely based on history taking. Patients suspected of a TIA require an urgent assessment with timely start of antithrombotic therapy to reduce the risk of an early ischemic stroke. Continue reading
Developmental Coordination Disorder (DCD) is often characterized as a skill acquisition deficit disorder. Continue reading
Chapel Hill Consensus Conference (CHCC) is a nomenclature system (nosology). It is neither a classification system that specifies what findings must be observed in a specific patient to classify that patient for clinical research nor a diagnostic system that directs clinical management. Continue reading
The original Gell and Coomb’s classification categorizes hypersensitivity reactions into four subtypes according to the type of immune response and the effector mechanism responsible for cell and tissue injury: type I, immediate or IgE mediated; type II, cytotoxic or IgG/IgM mediated; type III, IgG/IgM immune complex mediated; and type IV, delayed-type hypersensitivity or T-cell mediated. Continue reading
The Edmonton Obesity Staging System (EOSS) is a novel risk-stratification system that classifies obese individuals into 5 graded categories, based on their morbidity and health-risk profile. Continue reading
Foot ulcerations are among the most complex and heterogeneous complications in patients with diabetes. Skin ulcers need to be managed in different ways dependent on their etiology and pathogenesis.
The 10 Saint Elian Wound Score System (SEWSS) categories is helpful in guiding treatment decisions based on severity subcategories.
Caustic substances injure tissue by means of a chemical reaction on direct physical contact. Often thought of as acids or bases, caustics broadly include desiccants, vesicants, and protoplasmic poisons. The term “corrosive” is often used interchangeably with “caustic,” but corrosion implies a mechanical degradation, which does not always apply to caustics. Continue reading